Why Radiotherapy ? – Rationale :
• Proliferating fibroblasts
  are sensitive target cells
• Therapeutic efficacy for
   keloids, M. Peyronie etc.
• Positive clinical studies
• Long-term progression:
   ~ 50% @ 5 yrs require
   corrective hand surgery
Noninvasive Therapy of M. Dupuytren
6 months
3 years
2 years