Follow-up data presented at "New Frontiers in Dupuytren Disease", a symposium in Leuve, Belgium, in March 2012 showed that the initial good effect of tamoxifen vanished after a year and recurrence was about the same (if I remember correctly). I would not recommend taking tamoxifen because it has severe side-effects.
Wolfgang
Penny:... OR One who uses tamoxifen.
As quoted below by Dr. Eaton on usage of such.
"The most groundbreaking presentation was on the use of preoperative adjuvant tamoxifen to treat patients who had high risk for recurrence after a surgery. This randomized study showed that high-risk patients who had the preoperative treatment before limited fasciectomy for Dupuytren maintained their surgical correction to within about 10 degrees. Patients who were randomized to just the surgical treatment lost an average of 40 degrees of their initial correction.
The study used oral tamoxifen, but I’m considering a trial with topical tamoxifen. The big issues with patients who have aggressive Dupuytren are the extent of skin involvement and the dense relationship between the skin and the fascia as part of the biology. A minimal approach to straighten the fingers, followed by some sort of biologic intervention to maintain those results, would be great. " Penny
This nodule kind of piggybacks on a smaller nodule, which is attached to a cord--I don't think this one is involved with a cord directly. Mostly the ring finger, pinkey and middle finger are somewhat involved. The other hand is mostly corded on the ring finger and middle finger. Both have had NA done and are contracted again to stage 1. Penny
Had surgery yesterday, typing left handed so keeping it short. Removed the nodule and dup going to pinkey, ring &middle. Was not agressive in getting all the dup, because of the infection. Not in pain.
That is interesting. So, the surgery was for Dupuytren's and not just for the infection? Were there cords ("dup going to pinkey, ring &middle"). Please keep in touch with the forum about this. I am really surprised that the surgeon felt it necessary to do surgery.
The doctor wanted to make sure he got all the infection, so he removed some of the cords and the nodule without removing all for fear it might spread the infection.