| Lost password
5 users onlineYou are not loggend in.  Login
Research on effectiveness of RT protocols
 1
03/23/12 16:44
flojo 
Research on effectiveness of RT protocols

Thanks, Wolfgang, for reference the research on this site. Would you please put other URL links in this thread for other research related to dosage and results of RT for Dupuytren's? Lots of research is on this site, but you know all the research and can find pertinent research faster and easier than I can. It may help those who are weighing their RT options in making a decision to have links to research for RT in a thread.

People have their preferences about which protocol to use. For me, I prefer the least radiation that does the job. This research shows almost the same results after one year. We all have to wait for the 5 year results.

I am listing one URL address and quote only two parts of the article.

http://www.ncbi.nlm.nih.gov/pubmed/11172962?dopt=Abstract

Quote:
Prophylactic RT was randomly delivered; in Group A, 63 patients (95 hands) received 10 x 3 Gy (total dose, 30 Gy) in 2 series (5 x 3Gy) separated by 8 weeks; in Group B, 66 patients (103 hands) received 7 x 3 Gy (total dose, 21 Gy) in 1 series within 2 weeks. Orthovoltage RT (120 kV) was applied using standard cones and individual shielding of uninvolved areas of the palm. Relevant patient and disease parameters were equally distributed in both groups. Evaluation (toxicity, efficacy) was performed at 3 and 12 months after RT.

Quote:
CONCLUSION:

Both prophylactic RT concepts have been well accepted and tolerated by patients. Within the first year, they were equally effective to prevent further disease progression of DC and obtain considerable symptomatic improvement. Although 1-year results suggest similar response rates for both treatment groups, long-term FU of > 5 years has to be awaited for final assessment and recommendation of an optimized RT treatment schedule.

03/26/12 15:12
wach 

Administrator

Re: Research on effectiveness of RT protocols

Flojo, the 12 year results of that study are available as chapter 44 of the book by Ch. Eaton et al. (Eds.) "Dupuytren's Disease and Related Hyperproliferative Disorders" http://www.dupuytren-online.info/radioth...literature.html.

Wolfgang

03/27/12 05:44
flojo 
Re: Research on effectiveness of RT protocols

Thank you. RT for DD and LD is getting research behind it now. Please continue to point out the research as it comes available. I don't always get past the Forum.

 1

Imprint | Copyright | Privacy protection