Thanks, Wolfgang, for reference the research on this site. Would you please put other URL links in this thread for other research related to dosage and results of RT for Dupuytren's? Lots of research is on this site, but you know all the research and can find pertinent research faster and easier than I can. It may help those who are weighing their RT options in making a decision to have links to research for RT in a thread.
People have their preferences about which protocol to use. For me, I prefer the least radiation that does the job. This research shows almost the same results after one year. We all have to wait for the 5 year results.
I am listing one URL address and quote only two parts of the article.
Quote:Prophylactic RT was randomly delivered; in Group A, 63 patients (95 hands) received 10 x 3 Gy (total dose, 30 Gy) in 2 series (5 x 3Gy) separated by 8 weeks; in Group B, 66 patients (103 hands) received 7 x 3 Gy (total dose, 21 Gy) in 1 series within 2 weeks. Orthovoltage RT (120 kV) was applied using standard cones and individual shielding of uninvolved areas of the palm. Relevant patient and disease parameters were equally distributed in both groups. Evaluation (toxicity, efficacy) was performed at 3 and 12 months after RT.
Both prophylactic RT concepts have been well accepted and tolerated by patients. Within the first year, they were equally effective to prevent further disease progression of DC and obtain considerable symptomatic improvement. Although 1-year results suggest similar response rates for both treatment groups, long-term FU of > 5 years has to be awaited for final assessment and recommendation of an optimized RT treatment schedule.