There are posts and threads on this site. Surgery may
exaccerbate the nodules as healing occurs ("grapes to golfballs" in one post.) My feet burn and cramp at night.
Walking down steps barefoot causes a "burn." My interim
remedy has been gel sole inserts (Not Walgreen's variety.)
Topical (surface) remedies and/or food supplements are not
likely to remedy Ledderhose. I am able to run a few miles
comfortably and stand all day with a slight "burning" sensation. I hope it does not get worse. Sitting is not
a desirable option. Read up on Ledderhose. Good luck.

yes I also have the itching. My doctor explained it this way: when the tumors are growing they give off a histamine reaction similar to a bug bite. There is medication to block this reaction, but unfortunately I forget what it is called. If you contact your doctor he should be able to tell you. I tried the medication (a pill) a couple of years ago but had no relief from it. The only thing that works for me is to have the tumors removed. much luck

Unfortunately itching can often accompany *any* form of this disease. I believe it has to do with the formation of collagen. When you get a scab sometimes it will itch, which is telling you that healing of the skin is going on. With Dups and Lederhosen this is no different even thought the growth of collagen is run amok.

There is a Forum specifclly for Ledderhose at http://www.dupuytren-online.info/Forum_English/board.php?board=1

Randy