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ALCOHOL
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12/13/2015 12:17
staxman 
12/13/2015 12:17
staxman 
ALCOHOL

Does anybody have any info (scientific or anecdotal) on the role alcohol plays on the development OR progression of DD?
Thanks in advance.

    12/13/2015 12:36
    wach 

    Administrator

    12/13/2015 12:36
    wach 

    Administrator

    Re: ALCOHOL

    There is evidence that drinking increases the prevalence of Dupuytren's, i.e. people who are drinking more than 2 glasses of beer or wine per day are more likely to develop Dupuytren's http://www.dupuytren-online.info/dupuytrens_contracture.html . In a recent survey of Dupuytren patients the age of onset was investigated http://www.dupuytren-online.info/patient_survey.html . It turned out that drinking doesn't seem to have a clear effect on the age of onset. This means if you drink you are more likely to develop Dupuytren's but you won't get it earlier. People who are smoking are developng Dupuytren's significantly earlier.

    Wolfgang

      12/13/2015 12:45
      staxman 
      12/13/2015 12:45
      staxman 
      Re: ALCOHOL

      Is there any evidence/research on eliminating alcohol altogether and the impact on DD progression?

        12/13/2015 12:48
        staxman 
        12/13/2015 12:48
        staxman 
        Re: ALCOHOL

        that wasn't worded very well at all but you hopefully get the intent of the question.

          12/13/2015 13:01
          Stefan_K. 
          12/13/2015 13:01
          Stefan_K. 

          Re: ALCOHOL

          wach:
          There is evidence that drinking increases the prevalence of Dupuytren's, i.e. people who are drinking more than 2 glasses of beer or wine per day are more likely to develop Dupuytren's http://www.dupuytren-online.info/dupuytrens_contracture.html . In a recent survey of Dupuytren patients the age of onset was investigated http://www.dupuytren-online.info/patient_survey.html . It turned out that drinking doesn't seem to have a clear effect on the age of onset. This means if you drink you are more likely to develop Dupuytren's but you won't get it earlier. People who are smoking are developng Dupuytren's significantly earlier.

          Wolfgang

          I am not promoting the consumption of alcohol, but wouldn't it more careful and rigorous to talk about a correlation which has been found between the consumption of a certain quantity of alcohol and the occurrence of DD? Couldn't alcoholics and DD patients simply share common risk factors which favor both? And to spin it further, could it be that dealing with DD increases the consumption of alcohol? And what is the correlation between worrying about what one eats and drinks, and stomach ulcers and heart attacks?

            12/13/2015 13:35
            wach 

            Administrator

            12/13/2015 13:35
            wach 

            Administrator

            Re: ALCOHOL

            I don't think we are talking alcoholics. Those wouldn't get through the day with 2 glasses of beer or wine.

            If you have agressive DD and stop drinking alcohol, would that make a difference? Probably not because you already have DD. Would the DD become less agressive? Maybe, maybe not. Worth a try, you save money and your liver can relax for a while. Of course it also depends on how much you were drinking before.

            Wolfgang

            Stefan_K.:
            I am not promoting the consumption of alcohol, but wouldn't it more careful and rigorous to talk about a correlation which has been found between the consumption of a certain quantity of alcohol and the occurrence of DD? Couldn't alcoholics and DD patients simply share common risk factors which favor both? And to spin it further, could it be that dealing with DD increases the consumption of alcohol? And what is the correlation between worrying about what one eats and drinks, and stomach ulcers and heart attacks?

              12/13/2015 13:49
              staxman 
              12/13/2015 13:49
              staxman 
              Re: ALCOHOL

              Judging by your comments/suggestions, there's nothing definitive regarding the relationship between alcohol and DD. Suspicions, but that's about it. I was a two drink a day guy (probably a hair more) but I've been off alcohol for two months....since nodules appeared andIi got the diagnosis. I hope it has a positive result. Looking forward to hearing from others. Thanks, Wolfgang.

                12/13/2015 14:07
                Stefan_K. 
                12/13/2015 14:07
                Stefan_K. 

                Re: ALCOHOL

                Reducing one's intake of alcohol to a moderate level probably won't hurt and can do a lot of good to one's general health. I just wouldn't want anyone to believe that depriving him or herself of all alcohol is likely to have a significant effect on the expression of DD, based on available scientific studies. From my understanding one study has found a positive correlation between alcohol or DD, but not that alcohol increases DD as a cause/effect equation.

                Does anyone have the actual data on these 763 individuals aged 50 to 89 years in the Northern Netherlands in this study, of which as I understand 168 (22%) had some form of DD?
                With my background in analysis of research data I'd love to look at the data rather than the conclusions in the abstract. How many participants were there in the study who drank no alcohol, and what was the prevalence of DD for them?

                  12/13/2015 14:17
                  staxman 
                  12/13/2015 14:17
                  staxman 
                  Re: ALCOHOL

                  I'm with you, Stefan. I'd love to see that information.

                    12/13/2015 14:23
                    wach 

                    Administrator

                    12/13/2015 14:23
                    wach 

                    Administrator

                    Re: ALCOHOL

                    Why not contact the author, Dr. Rosanne Lanting? Her email address is on the abstract. As you are interested in that subject you might also contact Alexis Descatha, who found a correlation between (heavier) drinking and Dupuytren disease in a French stduy (GAZEL) http://www.ncbi.nlm.nih.gov/pubmed/24477316.

                    Wolfgang

                    Stefan_K.:
                    ...
                    Does anyone have the actual data on these 763 individuals aged 50 to 89 years in the Northern Netherlands in this study, of which as I understand 168 (22%) had some form of DD?
                    With my background in analysis of research data I'd love to look at the data rather than the conclusions in the abstract. How many participants were there in the study who drank no alcohol, and what was the prevalence of DD for them?


                    Edited 12/13/15 16:24

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