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Forum for Dupuytren's and Ledderhose 
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  • Any progress with the drug Humira as a treatment?
    • Any progress with the drug Humira as a treatment?
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    10/11/2020 20:45
    jazb 
    10/11/2020 20:45
    jazb      		Any progress with the drug Humira as a treatment?

    Curious if anyone has heard of any trials or progress in the research of the anti-TNF drug adalimumab (Humira) as a treatment option.

    I read something a few days ago that suggested this was being studied and had promising results. It seems that it was from a few years back though.
    10/12/2020 04:59
    spanishbuddha 

    Administrator
    10/12/2020 04:59
    spanishbuddha 

    Administrator

    		 Re: Any progress with the drug Humira as a treatment?

    jazb:
    Curious if anyone has heard of any trials or progress in the research of the anti-TNF drug adalimumab (Humira) as a treatment option.

    I read something a few days ago that suggested this was being studied and had promising results. It seems that it was from a few years back though.
    The trial is finished, results were due this year but their webpage now says 2021 https://ridd.octru.ox.ac.uk/ and phase 2a paper is here https://www.researchgate.net/publication..._Clinical_Trial

    Edited 10/12/20 08:08
    10/12/2020 05:42
    wach 

    Administrator
    10/12/2020 05:42
    wach 

    Administrator

    		 Re: Any progress with the drug Humira as a treatment?

    Many trials have been postponed/extended due to Covid. Might be the case here, too. I am sure they will present results on the International Dupuytren Conference in 2021.

    I myself am using Adalimumab from Humira to treat my Rheumatoid Arthritis (RA). While it so far works excellently for my RA, I haven't observed any effect on my bent Dupuytren finger. A pity, I would have loved that side effect ... Might be that the statement on
    https://www.dupuytren-online.info/dupuyt...s_research.html
    is true: "Further studies are required to analyse the effect on Dpuytren contracture, its possible improvement or slow down, and potential side effects."

    Wolfgang

    Edited 10/12/20 13:08
    10/12/2020 13:01
    jazb 
    10/12/2020 13:01
    jazb      		Re: Any progress with the drug Humira as a treatment?

    Thanks for the responses.

    Everything that I have read suggests that it would not reverse any current state of the disease; instead possibly halt any further progression. Seems it may be a treatment for very early treatment or post op to prevent recurrence.

    🤞
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