I started taking Biotin at the end of Aug. I have been diagnosed with DD for 10 years and am now 50. Had a surgery and and N/A. About the middle of Oct. new knodules and cords started popping up all over and the degree of contracture has increased in both hands a lot. I Am sched. for a couple of N/As and radiation in a few weeks. The other day I got to thinking about the Biotin. I know that Glucosamine is a no-no, but do you think Biotin might have something to do with this sudden increase in symptoms?