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Dupuytren's and weight lifting
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02/20/13 22:29
Randy_H 

Moderator

02/20/13 22:29
Randy_H 

Moderator

Re: Dupuytren's and weight lifting

Yes it does.

Personally I believe that the elevated swings of blood sugar from diabetes is stressful on a lot of our organs. It may be stressful to hands that are genetically predisposed to Dups. For that and other reasons (weight control) I eat low cab. If there is a reverse connection between Dups---->Diabetes we would all do well to kill the sugar.

03/19/13 07:35
stephenp 
03/19/13 07:35
stephenp 
Re: Dupuytren's and weight lifting

I also go to the gym 3x per week but do not do heavy work that stresses my hands, particularly palms where there are nodules and cords. I tend to use lighter weights with more reps.

I have noticed that after a lot gardening, using a spade or crowbar, my hands ache but maybe they would have ached anyway.

I am not aware of any papers that show a genetic linkage between DD and diabetes ie that people with DD are more likely to get diabetes. Type 2 diabetes is more a lifestyle disease associated with obesity. Type 1 diabetes has strong genetic linkages.

03/19/13 08:46
Seph 
03/19/13 08:46
Seph 

Re: Dupuytren's and weight lifting

stephenp:
I also go to the gym 3x per week but do not do heavy work that stresses my hands, particularly palms where there are nodules and cords. I tend to use lighter weights with more reps.

I have noticed that after a lot gardening, using a spade or crowbar, my hands ache but maybe they would have ached anyway.

I am not aware of any papers that show a genetic linkage between DD and diabetes ie that people with DD are more likely to get diabetes. Type 2 diabetes is more a lifestyle disease associated with obesity. Type 1 diabetes has strong genetic linkages.
It is my untested hypothesis that there is Type 1 and Type 2 DD. Type 1 being genetic as with Type 1 Diabetes and Type 2 being lifestyle. It seems to me that this might explain why people with diabetes have a statistical link with DD and why the older you are the more likely you are to have DD.

It would be interesting to do a survey of those using this site. I suspect we would find that those with both DD and LD and/or those with strong family history of the disease tend to get it younger and that the disease is more aggressive. I would put this in the Type 1 category.

Others with little or no family history and with only one or two fingers affected or one hand affected I expect to be older with a slower progression. I would put in the Type 2 category. Here I would expect to find environmental or lifestyle factors playing a part. Anecdotal evidence from comments on this site seems to indicate that many in my Type 2 category have other illnesses or injuries that may be acting as a trigger.

But then I have no medical or science training and this is an untested hypothesis.

03/19/13 12:02
zinkadoodle 
03/19/13 12:02
zinkadoodle 
Re: Dupuytren's and weight lifting

Seph, I think I would put myself into some kind of hybrid Type I & II, as you described them. When I first developed DD about 12 years ago at age 50, I never heard of the disease, had no family history that I knew of, and was completely surprised by it. However, I was also undergoing physical therapy for some kind of tendinitis, which was causing me all kinds of misery and pain. Was that causal? Who knows. But it surprised my doc and the therapists as to how fast it was progressing. I ended up in surgery to remove the cords and nodules from my hand, which was about 30 degrees contracted on my ring finger at the time. While the surgeon was in there, he did a tendon release for miserably swollen tenosynovitis of my ring and middle fingers. That was my left hand, and it's been fine ever since, except for a cord and nodule at the base of my thumb, which developed just post op. But, that never contracted and never bothered me, so I continue to ignore it.

Then, about two years ago, at about the same time that DD and now pronounced contracture started developing in my right hand, my twin sister also shows signs of DD. But, so far, all she has are some do nothing nodules on her palm. She's in a kind of wait and see mode. So now there is a family history.

My sister does not have any kind of accompanying tendonitis. I don't have any accompanying tendonitis this time. My right hand is contracting like gangbusters, with pronounced large nodules and cords running up three fingers. The most severe is my ring finger, which is somewhere around 40 degrees right now. My sister's hand is doing fine with no contractures. Neither of us are weightlifters or golfers, or heavy construction workers. She's a midwife and I'm a landscape architect. The only connection I can see is familial.

Monday of next week I see the hand surgeon for the Xiaflex multi cord clinical trial intake (if they don't postpone it AGAIN). I'll likely get the injections the following week. I just want to put this behind me. And, there's no way I want this to progress beyond 40 degrees. It's already screwing up my daily functioning. How some of you have endured more major contractions is something I hope I never see, but my heart goes out to you, and my hat's off to you. This is one lousy, insidious disease. ~ Diane

03/19/13 14:44
Seph 
03/19/13 14:44
Seph 

Re: Dupuytren's and weight lifting

Diane; Chin up. Remember this is the good disease. seriously irritating but you don't die from it.

My 19 year old daughter attended a small private school in Sydney. Since finishing high school in November 2011 she has seen the parents of 4 of her friends die. We attended the funeral of one of these parents last week.

Given the alternatives I feel lucky.

And yes maybe your are a hybrid of my Type 1 & Type 2 but more likely my Type 2 category. You say first developed at 50 with no family history. I see that you sister has it but given she is a twin so there will be lots of common environmental and lifestyle linkages. By comparison I am 4 years younger than you and I have had this for 45 years or so. And while I seem to have the most aggressive case in my family DD and LD do pepper my siblings and other relatives.

03/19/13 15:50
zinkadoodle 
03/19/13 15:50
zinkadoodle 
Re: Dupuytren's and weight lifting

Thanks, Seph. Of course, you're right. There are way worse things to have. Doesn't diminish the misery of this, however, and we have to deal with it as it comes. As far as diseases go, my psoriatic arthritis is WAY WORSE. I take Enbrel injections 2X/week, and have been doing so for over 10 years. If I stop, my hip pain becomes so intense, I can hardly walk. With Enbrel, I could abandon the cane. Very cool stuff, in my opinion. It changed my life. So yes, I do hear ya!! ~Diane

03/20/13 00:54
stephenp 
03/20/13 00:54
stephenp 
Re: Dupuytren's and weight lifting

I have also wondered about possible eitiologies and genetics. I have a strong family history (father and 2 brothers with DD) with the disease manifesting itself around the mid 50s. There is another set of DD patients who seem to relate the onset to trauma and where there is no genetic history (that they are aware of). However, with both types, there seems to be feral fibroblasts inappropriately laying down collagen.

Regarding diabetes, type 1 diabetes is early onset (<25 years) autoimmune related (destruction of beta cells) with a strong genetic link.

Type 2 diabetes is related to insulin metabolism/receptors, later in onset and more related to lifestyle than genetics.

I run a research centre focussed on wound healing and have contemplated some form of DD study, collecting epidemiological data as well as some cell biology study, hence my questions on biopsies on another thread.

02/15/14 23:44
janmatthews 
02/15/14 23:44
janmatthews 
Re: Dupuytren's and weight lifting

I do weight lifting at the gym and find my wrists feel weak and sore. (I have been weight lifting for 30 years). I had a double carpal tunnel release nearly two years ago and since then my DDs have appeared. Because of my DDs I use two pair of gloves at the gym but feel I need more wrist support. Has anyone else felt they needed more support at the wrist when working out, or maybe its related to my carpal tunnel issue? Look forward to feedback.

02/16/14 05:49
Seph 
02/16/14 05:49
Seph 

Re: Dupuytren's and weight lifting

janmatthews; Weightlifting has been part of my exercise program for more than 45 years. I alternate heavy weight sessions and high repetition 3-4 times per week. DD contracture and lots of nodules that cause all sorts of little problems with both hands but no problems with my wrists at all.

05/16/20 17:29
Jamba90 
05/16/20 17:29
Jamba90 
Re: Dupuytren's and weight lifting

JanMathews - this is a very old string and I imagine you may have moved on. I am relatively new here, but do have wrist pain above my Non-Dupuytrens hand. Only in certain positions.

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