In 2011 Surgery caused my DD to become active from just 1 pinky finger slightly affected to include three fingers curled to a fist after surgery. In my experience Xiaflex helped straighten out all three fingers even with all the painful reactions from the injection.

Some would argue that surgery and xiaflex are both trauma to the hand.

Last year had hip joint replacement on both hips. There was a lot of trauma to my hand with all my weight on the DD hand gripping canes and walkers. I wore a Fixxglove every night even though some new nodes formed and others became larger and very painful. I massaged my hand with a home use ultra sound and used a hot wax hand spa to relax the hand. I still wear the fix glove and no fingers have curled and my hand is functional.

Whatever the treatment in my experience DD can turn on a dime become active or become inactive. DD is always there in my case, therefore I am cautious .

Hi. The progression of DD is rarely linear - one of the reasons it is difficult to attribute its course reliably to specific events. We are tempted to consider certain observations as the results of others because they occur simultaneously or in chronological sequence, especially if the cause-effect relationship appears logical to us or confirms our beliefs. The progression can stop or even recede, and we will look for what other changes have occurred in our lives, e.g. in diet or exercise, or in this case, splinting. I, for instance, am tempted to attribute the halt in the contracture of my pinky to the consistent wearing of a night splint for the past three years. But it may well have halted by itself, or solely due to radiotherapy. A splint may not always be effective, but if designed properly should not cause trauma, certainly not the kind that through bleeding would generate collagen and worsen the disease. My 2 cents for today :-).

Stef

[56, Dupuytren diagnosis 2006, RH contracture and PNF/NA 2014, radiotherapy RH 2015, LH 2017 & 2018, night splint glove RH since 2015]