| Lost password
644 users onlineYou are not loggend in.  Login
Ages when Dupuytren's Strikes
 1
 1
06/09/2009 19:20
marsoft 
06/09/2009 19:20
marsoft 
Ages when Dupuytren's Strikes

Hi,

It seems I am a bit outside of the normal ranges. I first started showing symptoms in my late 20s (I am 39 now). I noticed from the graphs on another page that this is a bit unusual to say the least. I have not seen any literature on how this effects likelyhood of recovery or the period between a relapse. Anyone seen any information along those lines?

Regards,

Jason.

06/10/2009 01:11
deeproot 
06/10/2009 01:11
deeproot 
Re: Ages when Dupruyten's Strikes

Mine started when i was 24 now 33. I dont know of any information that will detail progression as every case is different. I did find some info surfing the internet about percentages of age groups and disease diagnosis. I cant recall where the information was. I am surprised that the medical community still doesnt understand what even causes the disease, only conjecture.
This link does contain a lot of information about the disease:

http://books.google.com/books?id=6c4-PmO...mp;dq=dupuytren's+and+glycogen&source=bl&ots=KyVyP22keN&sig=Q979YjIrGOZ9drFIBC8YOVhpyEA&hl=en&ei=oRUvSvX0KpfoMKra8PcJ&sa=X&oi=book_result&ct=result&resnum=1

06/10/2009 05:08
Wolfgang

not registered

06/10/2009 05:08
Wolfgang

not registered

Re: Ages when Dupruyten's Strikes

A short note (chapter 8.4) in Moermans' thesis reports

"Hueston nevertheless states that an early onset of the disease is a sign of a stronger diathesis and McFarlane et al. (1990b) found that patients whose disease has started before the age of 45 develop more recurrences."

The McFarlane et al. citation is

McFarlane R M, Botz J S (1990) (b)
The results of treatment. In: McFarlane R M (ed) Dupuytren's Disease. Churchill Livingstone, Edinburgh, pp 387-412

You probably would need a library to find this book.

Wolfgang

06/10/2009 07:08
Mike

not registered

06/10/2009 07:08
Mike

not registered

Re: Ages when Dupruyten's Strikes

I got told similar both by my doctor and this forum

I was diagnosed when I was 22 (now 24) and was told before my surgery that being younger than average would probably make it more aggressive in terms of how fast the contracture progresses.

However from what iv read this is a theory rather than fact as there seems to have been little study on how age affects things

06/10/2009 07:22
Wolfgang

not registered

06/10/2009 07:22
Wolfgang

not registered

Re: Ages when Dupuytren's Strikes

I believe there is also a very strong individual variation, statistics don't tell that much. A couple of years ago on a German Dupuytren symposium a surgeon told a story about a colleague who developed her first nodule at the age of 60. It progressed very slowly and never contracted severely. But at the age of 80 she developed another nodule in her other hand. That contracted the affected finger within a year. A completely different reaction even for the same patient. The doctor concluded: "What was the reason for this different behaviour? I wish I knew!".

Wolfgang

06/10/2009 15:16
marsoft 
06/10/2009 15:16
marsoft 
Re: Ages when Dupuytren's Strikes

I gotta say the different rates of the development of the condition is strange to say the least.

It started in both hands at the same time for me. The right hand just developed a little thickening and a small nodule that dimpled the skin above it (nearest my ring finger). My left hand progressed swiftly to its current contracture of around 30 degrees well within a year. Since then it has not progressed at all, in any way I can notice.

It is frustrating not knowing why the different rates on the different hands and why it stopped progressing. Makes me worry a lot about the procedure (which ever I end up going for, leaning towards NA). The procedures obviously cause damage to the hand, and I read that damage to the hand "may" be a trigger.

06/10/2009 15:21
Wolfgang

not registered

06/10/2009 15:21
Wolfgang

not registered

Re: Ages when Dupuytren's Strikes

Most likely the healing process is the trigger. But NA is minimal invasive and won't trigger growth elsewhere. It's more an issue of classical surgery.

Wolfgang

Quote:



... Makes me worry a lot about the procedure (which ever I end up going for, leaning towards NA). The procedures obviously cause damage to the hand, and I read that damage to the hand "may" be a trigger.


 1
 1
result&ct=result&resnum=1   glycogen&source=bl&ots=KyVyP22keN&sig=Q979YjIrGOZ9drFIBC8YOVhpyEA&hl=en&ei=oRUvSvX0KpfoMKra8PcJ&sa=X&oi=book   progressing   Dupuytren   dq=dupuytren   percentages   contracted   developed   Livingstone   nevertheless   information   progressed   Dupruyten   Strikes   progression   contracture   different   recurrences   disease   McFarlane