Hi, I’m thinking about RT for my dupuytrens . From reading and telephone conversations with radiation clinics there seems to be several different ways of administering the RT. Here are three that I have found. 1. 5 days of RT, 6-8 weeks off, 5 days of RT. 2. 7 treatments of RT in 5 days. Basically Monday through Friday, with 2 treatments on Tuesday and Thursday. 3. 5 days of RT, weekend, 5 days of RT Treatment plan #1 was perfected by the Germans, they seem to have the most experience using RT for dupuytrens. There are clinics in the US that follow this protocol, but they are out of my area. Treatment plan #2 is used at the University of Oklahoma. It only takes a week. Treatment plan #3 is used at Scripps hospital in San Diego. I live in San Diego. So, are there any significant differences in these treatment protocals? My gut instinct is to trust the German protocol, because they have the most experience and published material/studies. There has to be a real good reason to break up the treatments with a 6-8 week break. The Dr. I spoke with at U of O said there are radiation equivalency charts, which dictate different treatment protocol that are all basically equal. He said I should not concern myself with the differences. Dupuytrens has badly affected the strength and dexterity of my left hand,( it has literally started shrinking) if the same thing happens to my right hand I would be out of work. I am definitely considering RT, but need to know which plan to pick. Thank You Bob
Why not ask Prof. Seegenschmiedt in Hamburg or Dr. Keilholz ...
They seem to have seen patients for over 20 years; as far as I understand its important to block the FIBROBLAST growth - and the doses to do this seem to be higher than for other benign conditions for which radiation is used. Giving the full dose within a short period seems to ENHANCE the ACUTE SIDE EFFECTS, and that has been described in 2001 by Seegenschmiedt ...
I am personally convinced that a slower concept seems more appropriate as we are not dealing with a fast growing cancer ! And that's the reason radiation concepts are fast, every day ertc ...
I asked Dr. Seegenschmiedt about the two treatment options and he told me that they preferred the first approach as the gap provided time for the body to recover from the radiation, which it will do with the low doses that are used on your hands.
Think of it like spending 5 days in the sun for 4 hours each day and then 6 weeks indoors to recover and then repeating the process with 5 days in the sun again for 4 hours as compared to spending 5 days in the sun for 8 hours each day. No real hard data but the doctors feel that lower dosages spread over a longer period of time is probably safer.
At the time of my XRT in Essen the type 2 schedule took about 14 calendar days with treatment every other day at the higher dosages and you needed to factor in the weekend to arrive and the weekend between the two weeks when treatment would take place.
cureall:Can someone tell me: I have nodules and cords on my left hand...but no contraction....would rt REDUCE these nodules? Or does it just prevent future nodules?
Many people on here who have had RT reported a reduction in nodules for feet and hands. I had RT but there has been no reduction in nodules at all. No new ones either and the RT was done at the time there were physical changes occurring in my hand.
So YMMV from what anyone says.
I think the aim of RT or the effect is to slow or halt progression of nodules, and cords, so a reduction if you get one, especially in the feet is an extra.
That treatment option in Oklahoma sure sounds the most efficient! For those who are workers...
My situation: I'm 59 with nodules and cords on left hand, no contraction, and can't decide if I should spend around 5K for RT. I hate to shell out the money if my Dupuytrens just stays the same on its own. There has been a slight increase in nodules, but overall, it really hasn't gotten worse. It doesn't run in my family etc...I'm at that weird grey area, to RT or not to RT...I actually went to have it done at Vanderbilt in Nashville and had to wait so long I just left. The idea of spending 5K on this just bugs me! Plus the insurance will be paying probably God knows what! The medical health care system in the U.S. is so horrible in terms of costs. And flying to Germany for 14 hours TWICE???
Any insights into my predicament? I'm doing transdermal verapamil for about two months now with no decrease or softening, but it could be early... cureall