Well, I've got it all: full blooded Swede and a supplement taker. I took gluco/chon for years for osteoarthritis and they were a miracle. Now I'm paying the price with rampant DC and Peyronie's disease. I intuitively thought that gluco/chon might have contributed so I stopped for a month and my symptoms seemed to abate a bit. Then I started again and the symptoms worsened. The bottom line is (although the evidence is anecdotal) that I personally am convinced of the connection between DC and gluco/chon. Any DC sufferer should consider stopping these supplements.

Yeah, I'm not too thrilled with these two conditions that seemingly have no cure. At present I'm using DMSO and Vit E (both topical and pills) with little or no change apparent. I haven't tried isoflavoes, but that is next. The PD is new, only about a year but I've had Dupuytren's for years and have only recently (two months ago) tried the DMSO and E. Time will tell I guess. Thank god I have an understanding and sympathetic wife.

I started taking Glucosamine/Condritin a few months after a trip to Spokane in 1999 left me with irritated knee joints. Soon after I noticed small nodules and pits in both palms. I don't know if the G/C helped the knee condition as I stopped when the bottle was empty. A few years later (2002) I started getting soft tissue joint injuries when I took up mountain biking at the age of 47 and I started taking the supplements agin. I immediately noticed an increase in the deformities in the Palms but wrote it off to calluses.

When I took my son for a follow up visit with his hand surgeon, I showed it to him and he diagnosed it as Dupuytrens. I never made the connection until visiting this forum but the numbers are just too big for this to be a coincidence. BTW, before I wa diagnosed and getting no real help from the G/C, I switched to Proline / Lysene supplements and this did help the wrist injuries quickly an significantly. Until I get more answers on the Duo though, I have halted these supplements also.

wow...thanks for sharing the results of your search for more info...i am taking hawthorn berry and now will have to consider whether i should continue. But thanks for the info, this is where i am searching, how the type III collagen is deposited...have to learn more about the metabotlic process, even down to the cellular or molecular level! What a complex process. i still think someday soon we will find the missing link of why DC starts. one thing is - why are younger and younger people getting this. it's too bad Dup isn't a more of a priority in the research world. well, we'll just do it ourselves!

Hi Bill,

I have no way of knowing if you had participated in the recent survey, but so far you appear to stand virtually alone in your conclusion that Glucosamine had no effect on your D/C.

As for the Viking connection: you probably are confronted with a double edged sword: that of having at least 1 dominant gene present in a parental side. Taking your unusually high incidence of recurrence into account, it is also likely that your other parent may also be the carrier of a dominant gene? If you have no familial incidence of D/C, then I would assume that both sides carried recessive genes, like just about everyone else of northern or central European ancestry. Your Viking ancestors were great pillagers, however I think they had quite another agenda in mind. (No offense meant.)

If the aforementioned hypothesis is correct, then your use of items such as certain vitamins, supplements, lotions or for that matter any item that contains Aloe or collagen, or in fact arthritic ointments could have contributed to your continuing problem with Dupuytren's.

Make a list of products that you ingest as well as all contact items and you may quickly learn the cause of your problem. Besides, don't lose sight of the fact that surgery begets more surgery due to an excess release of collagen, that in turn produces scarring.

Good luck