Like several of you, I have been waiting for years for the phase III trial to begin. I recently corresponded by email with Dr. Hentz, who wrote on 5/11 that, "A recent communication indicates that drug might be available by August." This doesn't sound as convincing as the news regarding the trial posted in an earlier message.

What is the perceived advantage of having collagenase injections to allow "snapping" DD/DC chords? Is it the
U.S. delivery site? Now that Dr. Eaton and others are
offerring NA in the US, has the "demand" for collagenase
decreased? I am curious. If a remedy exists and is effective
for similar cost and outcomes, what are the issues?
Pros and cons anyone? Neither approach is a cure.
Thanks and apologies to LD, PD sufferers, who may truly
benefit from Biospecific applications. They do not "need"
NA. They do deserve support from the larger community IMO.

Assuming Auxilium is not using Collegenase as investor bate, and that approval for Peyronie's is achieved first, what about the fact that, once approved, many drugs are used "Off Label" once other uses for them are discovered. Neurontin is a good example. Approved as an anti seizure med, it is now used primarily for nerve pain. Will the FDA care where you inject the Collegenase once approved for PD? Surgeons want this option for DD, and if allowed to use it legally, they would.

I doubt Auxilium is aware of the NA movement, as it is really limited, for the most part, to this site. Five US surgeons offering it is nothing. There is no buzz yet. That will not happen until Eaton presents in 2006.

Where NA is effective, there is no advantage over Collegenase I can think of. However, I'd love a Collegenase injection of two to dissolve these painful Dups tissue in my palm.

Well J, as many of us know "first Hand", something has---> NA. In spite of it's limitations and drawbacks, at least the World is finally going to have it's first meaningful alternative to OS in 50 years. While I'm greedy for more and better options, at least we can count NA among our blessings on our still fully operational fingers.

For Jim h

I am a member of Ledderhose - Yahoogroups.com
I posted details of the Paris practioners on this site. Shortly after my posting a lady from Portugal posted that as a result of my info. she had postoned foot surgery for her son and instead got him into Dr Lermusiaux. Lermusiaux performed NA on his foot. She wrote that her son walked out of Lermusiaux's door without any discomfort and was thrilled with the results and the fact there was no tradtional surgery. Another convert!!