Interested to know whether members of this site have ever been diagnosed as b12 deficient (pernicious anaemia) or as having a high homocysteine level.



Thank you

Thank you Wolfgang. I will search the site.
The reason I ask the question is that b12 deficiency (in most cases) causes homocysteine (HcyH) to rise. A high HcyH affects the collagen balance in the body. Lab studies of DD sufferers shows that collagen levels are out of balance. Further, severe B12 deficiency, as well as many other health issues, will cause problems in accurate cell replication, usually noticeable with bowel problems and possibly burning mouth Syndrome (BMS) because of the frequency of cell replication required in the digestive tract. Hcyh rises early on in deficiency, although some patients may never be diagnosed as B12 deficient, because their serum B12 is normal. However, their Hcyh level may be raised. Like DD, B12 deficiency can have a genetic link.

I should be interested to hear from anyone who has elevated Hcyh, has had a diagnosis of B12 deficiency or possibly both.

Thanks again

Megan:

---

This post caught my eye. My maternal grandmother, who had Dupuytren's, had to receive regular injections for B-12. Around the same time as I was diagnosed with Dupuytren's, I noticed one day that I had these purplish vertical stripes in almost all of my fingernails. I don't know why I hadn't noticed them before, or for how long they had been there.

I started searching around the internet, and found some photos and descriptions of fingernails of people with b-12 deficiency and some of the photos looked exactly like my fingernails. I started taking B-12 (I didn't see a doctor) and the stripes on my fingernails eventually disappeared.

I stopped taking B-12 about two years ago...maybe I should continue...as a prophylactic!

Megan L, Bellevue, WA

I have to take mega dose of folic acid daily (3 mg) and B12 daily as suggested by a physician years ago. I assumed it had to do with homocysteine level and heart attack at age 38. I have Ledderhose (severe) and knuckle pads.
What more do you know about this?
Thanks!