I am 41 and was first diagnosed with DC when I was 17, when a small itchy lump formed in the tip of my left pinky. I have had 3 operations, when I was 18, 20, and 24. The last two operations also had skin grafts.
The surgeon was one of the top Orthopedic's in Australia.
After the first op. I was told the chance of re-ocurrence was 26%. I used a splint, however DC returned with avengance and I had a much worse condition within 3 months.
After 2 more op's the same result, and in the end the surgeon suggested amputation. I declined, as I wanted to look at other options first.
My finger gradually bent right over to the almost closed position, however the last 16 years it has not gotten any worse or better, and the DC was contained in the finger and had not formed in the palm.
Just recently an aggressive lump has formed in the palm on the tendon, and is very agressive, growing in size in a few weeks. I had recently changed my diet including an increase in Vitamin C and other antioxidents and vitamins, however do not take any medications and have not at any stage of my life.
It may be coincidental, however I am very keen to try some alternative remedies rather than have another operation!

Jim

Just got back from the doctor today. I have lumps in my left hand and it is very painfull. She tells me that it could be Dupuytren. I never hear of this before. Funny I started to take Glucosamine only about a month ago. I have had an episode of Rhumatoid arthritis more than ten years ago and lately when one of my joint in my left hand started to hurt, I started to take large doses of Glucosamine and Chondrotin. My nodules are just getting bigger and more painfull. I am not sure if it started before or after the Glucosamine. Now the doctor has given me Vioxx to try to releave the pain and swelling. Is this wrong to ??

Tonight I have been looking to find out about this disease and I found this topic.

Scarry, why does the healt organisation do nothing about warning people about this supplement.

What is the reommmended dosage for Glucosamine/Condritin?>
There are so many choices, I'm confused.

Charlie,
Many on this forum have reported more aggressive Dup.
growth after beginning to take glucosamine and chondrotin.
The consensus seems to be to avoid them and excessive
vitamin C.

Jane:

I don't know that there has been any research that provides a conclusive link between glucosamine and Dupuytrens, but if you look through the postings on this site over the last several years you will see overwhelming anecdotal evidence. Of course, every person seems to vary in how they respond to various triggers, and in the aggressiveness/passiveness of the disease. But, it would seem prudent for anyone with Dupytrens to avoid glucosamine.

Tom M