Steve,
Thanks for the information. I wish I had access to a medical library. The PubMed excerpts are interesting. It also shows how much research has been done with Dupuytren's. I'll keep reading.

Steve, I think that the "real" beneficieries of the
collagenase trials will be the Leddehose and Peyronies
patients. To date, they lack favorable outlooks; Collagenase
treatment may change that. The bonus for DD patients might
be an increased interval between re-treatment when compared
to NA. The trade-off will be the cost and time involved in
multiple visit injections. I am curious about the extent
to which the cord is "dissolved;" just enough to sever,
or is it eliminated? Either way, it will return. I suspect
that it is just a slower, chemical version of NA. Perhaps
it could be called EA (Enzyme Aponevrotomy.) Alas, I am
just guesing; we all await the final trial outcomes sometime
in the distant future. Then we can wait for the training
period while Doctors learn the technique. Eventually, the
procedure might be comparable to Botox injections. I will
tell my progeny to follow the progress. Fortunately, they
already speak French; should the autosomal dominant genes
manifest themselves sooner rather than later. they can go
to France for a few days, (or Italy, Belgium, Switzerland,
Florida or Tennessee.) The procedure takes 20-30 minutes
and currently costs about $250.00 US per sesion in Europe. Hotels, airfare, meals, museums and bateaux mouches are extra. Florida is an option and whilw more expensive,
might be more "handy."

The middle finger on my right hand has just started to come down after having DD for 8 years. I have had two lumps in my palm and a raised band running from the lumps to my finger. Some fingers bend slower than others.