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Forum for Dupuytren's and Ledderhose 
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  • Phase III trials at Standford Hand Clinic
    • Phase III trials at Standford Hand Clinic
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    01/15/2002 00:32
    Joe Williams

    not registered
    01/15/2002 00:32
    Joe Williams

    not registered

    		 Stamford Trials

    I have DC in both hands, rt small finder curled, had surgery 10 years ago, it came back in 30 days. I am seeing anothe Doctor in February as I now have painful bumps on the tops of some knuckles, I shall watch the Stamford trials closely as is in my backyard !
    09/30/2002 01:18
    Ron Winder

    not registered
    09/30/2002 01:18
    Ron Winder

    not registered

    		 dupuytrens contractus

    Have had d.c for twenty years .had surgery on both hands.leaving scars but gradually recerring.

    Have recently attended Docteur Jean Luc Lermusiaux surgery in Gagny Paris,

    local anaesthetic, two visits for thumb, little finger ( both very badly affected) third finger of left hand and little finger and third finger right hand.
    thumb left hand improved 90%. little finger 75%. third finger 100%(both left hand)right hand little finger 100%
    third finger 75%
    returning for third treatment Nov for more treatment little finger and third finger left hand, third finger right hand.

    most noticeable difference in surgical and non-surgical treatment is non-scarring and no loss of feeling in non-surgical. (aware of re-occurrence more than possible in both types but more chance of further treatment in non surgical)
    10/03/2002 01:15
    Sheryl Rose

    not registered
    10/03/2002 01:15
    Sheryl Rose

    not registered

    		 Stanford Trials

    Hi! I was just diagnosed with DC this morning and, in trying to find info about it, discovered this site. I am wondering what the outcome of the trials was and if anyone knows where I could get more info about them.
    Thanks,
    Sheryl
    10/07/2002 01:28
    Ben Beam

    not registered
    10/07/2002 01:28
    Ben Beam

    not registered

    		 Stanford Trials

    Sheryl, I have been accepted for the Stanford trials, and have been impatiently waiting for over a year for them to start. My telephone contact for this is Carolyn at 415-740-4601. She says the trials will start in January, but the start date has been pushed back a half-dozen times already.
    Ben
    10/07/2002 01:03
    Gary

    not registered
    10/07/2002 01:03
    Gary

    not registered

    		 Phase III trials

    Ben,
    What are the reasons for the delay? Is the delay from manufacturer or is the delay from a government body? There seems to be a problem somewhere. The price of the stock of Biospecifics has really struggled as though there is something wrong. Stock price should be soaring if drug showed the promise we are anticipating.
    Gary
    03/30/2006 01:32
    Red

    not registered
    03/30/2006 01:32
    Red

    not registered

    		 Collegenase

    Will the current Phase 111 trials also be held at Stanford? I assume they will be widespread. There were at the last attempt.
    05/04/2006 01:42
    Wolfgang

    not registered
    05/04/2006 01:42
    Wolfgang

    not registered

    		 Collagenase trial

    Rick, the results of the phase II trial have been published in 2002, e.g. as M. Badalamente et al., Collagen as a clinical target: nonoperative treatment of Dupuytren's disease., J Hand Surg [Am]. 2002 Sep;27(5):788-98. An abstract is e.g. at http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12239666&dopt=Abstract.

    The phase III trial has been pending for quite a while now and I wonder if it ever will be completed.

    Wolfgang
    05/04/2006 01:46
    JD

    not registered
    05/04/2006 01:46
    JD

    not registered

    		 Phase 3 trials

    Dont hold your breath.Phase 3 is postponed till October.If approved it will take several more years to come to market, got this information from Stony Brook.


    best wishes to all,

    JD
    05/04/2006 01:49
    jim h

    not registered
    05/04/2006 01:49
    jim h

    not registered

    		 phase III

    You can make money by selling products to customers, but you can make a lot more by selling hype to investors. And you can sell the same hype many times.
    05/11/2006 01:12
    Richard Nevle

    not registered
    05/11/2006 01:12
    Richard Nevle

    not registered

    		 phase III

    I heard conflicting information a couple of weeks ago from Dr. Vincent Hentz at Stanford, who indicated that the phase III trials could begin this summer. Who can I contact to get more definitive information?

    Thanks,
    Richard
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