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Forum for Dupuytren's and Ledderhose 
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  • Dupuytren~sq~s Contracture Research - NEW
    • Dupuytren~sq~s Contracture Research - NEW
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    10/12/2005 23:39
    Dr. Wicks

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    10/12/2005 23:39
    Dr. Wicks

    not registered

    		 Dupuytren~sq~s Contracture Research - NEW

    Allegheny General Hospital, University of Nebraska Researchers, Nebraska Medical Center in Omaha have identified the location of a gene on the human genome that is responsible for Dupuytren's contracture.

    Great news!
    10/12/2005 23:24
    jim h

    not registered
    10/12/2005 23:24
    jim h

    not registered

    		 Gene News

    I find a brief mention of this on their web site but no details. Do you know more?
    10/12/2005 23:50
    Stage One

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    10/12/2005 23:50
    Stage One

    not registered

    		 Gene News

    Dr. Wicks; thank you for this pertinent news. We will
    all look forward to future developments. Identifying the
    gene is a major step toward "understnding" the condition
    and appropriate treatment. Go Corn Huskers!
    10/13/2005 23:25
    diane 
    10/13/2005 23:25
    diane      		GO BIG RED

    As a UNL alum afflicted by dups i am thrilled to hear the news of the discovery of the gene causing it. Can someone direct me to the liturature reporting this finding?

    Diane
    10/13/2005 23:52
    Michael L.

    not registered
    10/13/2005 23:52
    Michael L.

    not registered

    		 Genetic Basis for Dup~sq~s


    Well, apart from a couple of errors of fact in the Newswire report, that is really terrific news! It can be only a matter of time now until they nail it down to a single gene. It's even great news that the basis of the disease, or at least some variants of the disease, is so simple as to be attributable to a single gene.

    But not all Dup's run in families. It may be that there is more than one genetic basis for it, as is true for cancers. And it may be a long time, if ever, until they can build upon the knowledge to create a therapy.

    - MML
    10/13/2005 23:47
    jim h

    not registered
    10/13/2005 23:47
    jim h

    not registered

    		 link

    Hammer head, can you give me a link to that story? I'd like to bookmark it.
    10/14/2005 23:42
    Hammer head

    not registered
    10/14/2005 23:42
    Hammer head

    not registered

    		 link

    http://www.prnewswire.com/cgi-bin/stories.pl?ACCT=104&STORY=/www/story/10-13-2005/0004167642&EDATE=
    10/14/2005 23:50
    Frances

    not registered
    10/14/2005 23:50
    Frances

    not registered

    		 Where to find it

    For those who prefer Google, search 'Center for Genomic Sciences' then click under 'Research' located at the top of the screen. It's article #8 called 'The Genetics of Dupuytren's Contracture.'
    10/14/2005 23:10
    jim h

    not registered
    10/14/2005 23:10
    jim h

    not registered

    		 gene

    Thanks
    10/15/2005 23:15
    marjorie 
    10/15/2005 23:15
    marjorie      		gene

    Don't get too excited yet. The gene itself has not yet been discovered, only the area. Like looking for a needle in a haystack.
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    appropriate   researching   responsible   localization   foundation   Researchers   publication   0004167642&EDATE=   Contracture   Allegheny   understnding   blackwell-synergy   Identifying   non-surgical   ACCT=104&STORY=   Dupuytren~sq~s   attributable   developments   institutions   Research