| Lost password
80 users onlineYou are not loggend in.  Login
The Real Deal?
 1 2 3
 1 2 3
11/01/06 01:58
Randy H.

not registered

11/01/06 01:58
Randy H.

not registered

The Real Deal?

I had a phone message left by the office of the UCLA surgeon who will be starting the Phase III trials up again. This is the *same* UCLA office that was on the verge of doing Phase III 3 1/2 years ago. Bios ran out of money back then. Now, however, since my name was on their old list, I got the call to see if I was a candidate.

If the money wasn't there to do phase III the UCLA surgeon would not be spending his time to start recruitment. In fact, this recruitment effort itself is funded by Phase III money. This UCLA surgeon was burned once by BioS, so he's not about to jump in again with being paid. Believe it.

When you get a message on your home phone for Phase III Trial recruitment it tends to make a believer out of you. I think this is the real deal.

11/01/06 01:16
Steve

not registered

11/01/06 01:16
Steve

not registered

Phase III

I also got a call this week from UCLA....too bad I won't qualify since my fix from Dr Eaton is still holding up.

11/02/06 01:23
Diane

not registered

11/02/06 01:23
Diane

not registered

Phase III

Thanks Randy and Steve for posting about the Pahse III trials and thanks Randy for getting the site cleaned up.

Can people call UCLA and volunteer for the trials and if so, could you post contact information? Anyone out there who participates, please share your experience.

11/02/06 01:36
Randy H.

not registered

11/02/06 01:36
Randy H.

not registered

Go For It

I have been given permission from the office at the UCLA medical center to post the contact number. The actual start of the trial is in a few months, but they want their candidates set up in advance. You must "live locally" (driving distance) because you will be required to make quite a number of return visits for examination. You have a 50% chance of initially receiving the placebo (you'll know because nothing will happen). The placebo group will then receive the real deal at the end of the study. The only cost will be for parking, which is about $10. They need about 10-15 more good candidates. I believe you must have a finger contracture of >= 45 degrees, which is the point at which OS is usually done. I also believe no prior surgery on that finger. Check with the office.

Jump on this. I would if I needed more treatment. Eaton's NA is holding up quite nicely for me after 2 1/2 years however, so I am not a candidate.

Be sure to say hi to Roy for me.

(310) 206-6337

Randy H.

11/02/06 01:45
jim h

not registered

11/02/06 01:45
jim h

not registered

deja vu all over again

Ok I think we went through this part at least once before. Patients with serious, progressive contractures are contacted and put on a "waiting list" for a trial. Months go by and nothing happens. It costs nothing for Auxilium to build this list of patients, who in return agree not to have real, available treatment like NA while they wait, indefinitely.

Obviously the trial hasn't actually started in any meaningful sense and as always, no real date has been given out.

11/02/06 01:49
Randy H.

not registered

11/02/06 01:49
Randy H.

not registered

Budweiser

Jim,

Just because you are a cynical and jaded doubter........that doesn't make you *wrong* :)

We'll sit back and see. If this is yet another false start I'll join the jim h Collagenase Doubter's Society :)

Otherwise you owe me a beer. How's that.

11/02/06 01:27
jimh 
11/02/06 01:27
jimh 
So is this the way it is?

Well of course I'm hoping to be proven wrong :-)


But I'm thinking that new people come to this forum hoping to get advice and information from fellow patients. So my advice, based on about 10 years of following this story closely, is this: if you're at the stage where you need treatment, do it now and don't get hung up waiting for AA4500.

Auxilium's invester presentations say it "could" be available in 2008, and that's probably the most optimistic statement they felt they could justify. So every time the trials are delayed, just mentally push that date back.

In the end, it's all about money, and Phase III is expensive. They can get patients and doctors identified but until they're really read to cut checks, it's just a Phase III trial on paper. Whether they can actually cut those checks will depend on their cash flow at the time. And even if they start the trial, that's no guarantee it will be finished.



11/02/06 01:17
steve 
11/02/06 01:17
steve 
So is this the way it is?

Stony Brook also confirmed the trial will start soon.

11/03/06 01:12
Randy H.

not registered

11/03/06 01:12
Randy H.

not registered

So is this the way it is?

AUXILIUM:

As you can see Mr. Investor, people are lining up in droves to be our Guinea Pigs for the *final* clinical trial of Collagenase. They all desperately want to avoid that nasty surgery, which is what makes our product such a GREAT investment. It's the same everywhere. UCLA, Stonybrook, Stanford and in Europe. All you need do is say the word "Collagenase" and they come running.
Say it with me now......'Collegenase......Collagenase.....Collagenase'. Good, I think you're getting it.........

What?......'N' What?.......Oh, 'NA'. Yes, we've heard about that French thing. It's dangerous and doesn't work. Just ask your local CHS, they'll set you straight, but with surgery of course. But there again, interest in NA just proves my point. People want to avoid that nasty hand surgery so they'll try *anything*. Yes, Mr. Investor, your 30 million is *far* better invested here than on that next Brad Pitt movie. He's getting a little long in the tooth don't you think?

:)

11/05/06 01:20
Wolfgang

not registered

11/05/06 01:20
Wolfgang

not registered

Spam

To the occasional visitor of this forum: revently this forum became heavily spamed. Don't get discouraged, there is still good stuff further down the list of threads. Only the top threads are heavily spamed.

You are also welcome to visit www.dupuytren-online.info which hosts a forum that is - so far - still free of spam.

 1 2 3
 1 2 3
Patients   treatment   bio-mechanical   recruitment   information   contracture   Auxilium   dupuytren-online   Dupuytren   Collagenase   understanding   presentations   contractures   qualification   ProtocolNumber=0   injection   participating   effectiveness   mechanically   bio-mechanically