| All cause increase in mortality |
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07/30/2026 09:12
TwisterSister
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07/30/2026 09:12
TwisterSister
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All cause increase in mortality
Hello all,
I am newly diagnosed with both Dupuytrens and Ledderhose, mid fifties and female. Not surprised as my Dad had it. I was not at all concerned by the diagnosis other than what I can do to help myself, while looking for physio exercises, I stumble upon a video with a Dr citing higher mortality risk especially from cancer. So I dig deeper, read papers and research material, still not happy with what I read and decide statistics are best left for those that understand them. I have failed to get any real life perspective on the actuall risk but am interested to know if anyone has some figures that a lay person can relate to. My father did die at 64 from colorectal cancer, but also smoked for years and drank heavily all his life. Any reassuring perspective would be appreciated. Thank you.
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07/31/2026 06:39
spanishbuddha  Administrator
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07/31/2026 06:39
spanishbuddha  Administrator
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Re: All cause increase in mortality
Hi Just remember that a statistical association with one condition to another is not really helpful in providing reasons for the association, without further analysis. See wikipedia 'Correlation does not imply causation'. https://en.wikipedia.org/wiki/Correlatio...imply_causation The Duputrens Research Group has a summary of some of the literature reporting these associations here https://dupuytrens.org/dupuytren-literature-mortality/ This probably doesn't help assuage your concerns, so just continue to live and enjoy your life, whilst following most, WHO or national or local, guidelines for your health (guidelines which in turn seem to change or be contradictory every decade or thereabouts)! Best wishes SB
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07/31/2026 13:54
rjfriki
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07/31/2026 13:54
rjfriki

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Re: All cause increase in mortality
To build off and support what SB is sharing: Yes, it appears from longitudinal research studies that there is an association between Dupuytren's Contracture and mortality; however, the following are the correlates: smoking, excessive alchohol drinking, diabetes, cardiovascular disease, metabolic disorders. So, I would focus more on the things you can control like not smoking or quite smoking, or not drinking excessively, having a healthy diet, staying active, etc... You get the idea - these are things you can control and change. I have Stage 4 right pinky contracture; it is hereditary and some relatives died early because they smoked and drank and were overweight; while others lived into their 90s and my maternal grandmother made it to 102, but they lived healthy life styles. Hope this helps.
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07/31/2026 20:44
TwisterSister
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07/31/2026 20:44
TwisterSister
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Re: All cause increase in mortality
Thank you both for your replies and pesrpectives. There is much common sense in what you are saying. I am sure worrying will not help any of us. I appriciate that we can only be responsible for our lifestyles and be proactive with our health. I also feel we owe it to ourselves to live our lives and not waste it on unnecessary worry and statistics. Thank you again.
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