It occurred to me that some drug usage is demand-drivened.
Is Bo-Tox FDA approved for facial wrinkles? I do not know.
I do know that people seek out practioners who use Bo-tox.
Lately, many have expressed justifiable appreciation for
Dr. Eaton incorporating into his repitoire, NA. Well. what
if he, or someone else offered collaganase injections?
The major deterrent is liability. As Phase III studies progress, final approval may be moot; i.e., more patient
driven than FDA appoved. How long must one wait before
entrepreurial, licensed, responsible, doctors say, "this
is off-label and it works with limited, pedictable side-
effects." Just what are we waiting for? Let us begin the inquiry. If Trial III status is not forth-coming, what
hardy souls are willing to take on a few limited cases to
test the effeciacy and reliability. This is a market driven
outcome. Problems find solutions. Collagenase sounds like a
solution. The econpomics of FDA aprroval and marketing souned more problematic than the the actual implementation as safety and protocol are established.
Bottom line: maybe trial III completion is not that esssential considering other off-label usage involving drug treatment for other recognized maladies. Read the drug insert for aspirin: "up to and including death?" The track
record suggests that aspirin can kill (Reyes syndrome,) still it is universally available.
Any opinions about going to Tiajuana for DD treatment?
What is the threshold level of confidence required?
Is health insurance a major factor in decision making,
even if finances are not (insurance covers it, so it must
be safe.) Are case studies and success more compelling?
Waiting for FDA approval may be secondary to obtaining
relief for motivatd individuals.

Stage1, I agree. The small risks of Collagenase injections don't justify the enormous cost and endlesss delays of FDA approval.

BSTC claims to have "proprietary understanding of collagenase production" and an "extensive patent position". So this form of injectable Collagenase will come only from them, and only when they can figure out how to make a lot of money from it, one way or another.

Would I go to another country for this treatment? After the misery of 2 conventional surgeries, my answer is YES. But the practicioner would have to know what he was doing. It has to be injected into exactly the right spots, in the right quantities.

Sean/Gary's comment here is totally biased and untrue.

jim h,
You are right. That is why I think it is a decision everyone has to make for themselves. There isn't a right or wrong decision that fits everyone.

Sean,

Don't be silly.

The fact that this sight exists is proof in and of itself that Dups surgery is a miserable experience for just about everyone unfortunate to require it. Why does this site exist in the first place? The main purpose of the development of these new far less invasive procedures is not to reduce reoccurrence. Nope, that's not it. The purpose is not to increase the profitability per procedure for those who are, and will increasingly offer them. Nope, that's not it. Do you read the flood of positive reports coming in almost daily from those thrilled with the results they are getting from Dr. Eaton? Why are they thrilled? Is it because they like Florida, or because they've learned that their insurance will cover NA? Nope, that's not it either. Read them again. And why would Dr. Eaton visit Paris to learn and begin to practice NA? Just a good excuse to write off is trip? Nope, that's not it. Study his web site a little longer. And what exactly would drive a company like BioSpecifics to invest millions and millions of dollars on a Dups surgical alternative? What makes them think patients might prefer an injection over a perfectly good and fully invasive surgery that's been around for over 100 years? Does it have anything to do with the fact that they've had to turn people away in droves wanting to get into these trials?. What's the matter with these people! Why don't these patients just cowboy up accept their surgical fate like men (or women)!!! And why would the top micro hand surgeons at Stanford, UCLA, Northwestern want to get on board and help get create an alternative to opening up and digging around in peoples hands?

Sean, don't be silly.

Merry Christmas