International Dupuytren Award
The International Dupuytren Award
The International Dupuytren Award recognizes exceptional scientific publications on research or clinical treatment of Dupuytren and/or Ledderhose disease. Research can be about treatment, epidemiology, pathogenesis, genomics, or other areas, like anatomy, improving the understanding and treatment of these diseases.
The Award carries a monetary prize of 1,000 EUR.
Who can participate?
The publication must be an original research paper that has been published in a peer reviewed journal or book and that has not yet been awarded elsewhere. The Award will normally be given to the leading (first) author but, upon request, the prize money can be split. Applicants can be physicians or scientists. Please submit only one paper per leading author, not several. We recommend to submit the paper that you consider presenting the most outstanding new research or clinical aspects.
Who will elect the winner?
The winner will be selected jointly by the Scientific Advisory Board and the Management Board of the International Dupuytren Society. The winner will be announced at the annual members‘ assembly of the Dupuytren Society or at another event selected by the Scientific Advisory Board. The International Dupuytren Award will be awarded annually but the Scientific Advisory Board may decide to waive the Award if the submitted publications for that year do not meet the criteria or do not score well enough when voted upon by the Board.
Deadline for submission
The award in a specific year is given for a paper that was published in the previous year. For example the Dupuytren Award 2010 was given for a publication of 2009.
Please submit applications for the 2025 Award (i.e. your paper published in 2024) latest by 31 March 2025 (deadline extended!), including
the submitted paper or at least its abstract should be in English. For submission in other languages please provide us with a translation.
- curriculum vitae of the author(s). Usually the CV of the first author is sufficient but if you intend to split the award, please submit CVs of all related authors.
Where to submit your application?
Please email your application to
dupuytren_award /at / dupuytren-online . info (please adjust this email address).
And the winners are …
International Dupuytren Award 2024
For Clinical Research:
Anneke de Haan, University Medical Center Groningen, The Netherlands,
for her paper Anneke de Haan et al.
„Radiotherapyy for Ledderhose disease: Results of the LedRad-study, a prospective multicentre randomised double-blind phase 3 trial”
Radiother. Oncol. 185 (2023) 109718 . Full text
For Basic Research:
Lisa Oezel and Vera Grotheer (jointly), Medical Faculty and University Hospital Düsseldorf, Heinrich-Heine-University, 40225 Düsseldorf, Germany,
for their paper Lisa Oezel et al.
„Dupuytren’s Disease Is Mediated by Insufficient TGF-β1 Release and Degradation”
Int J Mol Sci. 2023 Oct 11;24(20):15097. Full text
International Dupuytren Award 2023
For Basic Research:
Thomas Layton, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, University of Oxford, Oxford, UK.,
for his paper Thomas Layton et al.
„A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease”
Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2120336119. Full text
For Clinical Research:
Postdoctoral researcher at the University Medical Center Groningen, The Netherlands,
for her paper DC Broekstra et al.
„Disease Course of Primary Dupuytren Disease: 5-Year Results of a Prospective Cohort Study”
Plast Reconstr Surg. 2022 Jun 1;149(6):1371-1378 . Abstract
International Dupuytren Award 2022
For Basic Research (shared between two papers):
Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, University of Oxford, Oxford, UK,
for his paper Yoshifumi Itoh et al.
“A common SNP risk variant MT1-MMP causative for Dupuytren’s disease has a specific defect in collagenolytic activity”
Matrix Biology 97 (2021) 20-39 full paper
Centre for Inflammation Research, The Queen’s Medical Research Institute, University of Edinburgh, Edinburgh,
UK, jointly for their paper Ross Dobie et al.
“Deciphering Mesenchymal Drivers of Human Dupuytren’s Disease at Single-Cell Level”
J Invest Dermat 142 (2022) 114-123. Epub 2021 Jul 16.full_paper
International Dupuytren Award 2021
Lynn Williams, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, University of Oxford, Oxford, UK.,
for her paper Lynn Williams et al.
„Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300“
PNAS 117 (2020) 20753–20763. full_paper
and
Thomas Layton, Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, University of Oxford, Oxford, UK.,
for his paper Thomas Layton et al.
„Cellular census of human fibrosis defines functionally distinct stromal cell types and states“
Nature comm (2020) 11:2768 full_paper
For Clinical Research:
Oxford NIHR Musculoskeletal Biomedical Research Unit, Botnar Research Centre, University of Oxford, UK,
for his paper Osaid Alser et al.
„Serious complications and risk of re‑operation after Dupuytren’s disease surgery:
a population‑based cohort study of 121,488 patients in England“
Nature Sci Rep (2020) 10:16520 full paper
International Dupuytren Award 2020
For Basic Research:
Kennedy Institute of Rheumatology, Nuffield Department of Orthopaedics, University of Oxford, Oxford, UK.
for their paper
David Izadi, Thomas Layton et al.
„Identification of TNFR2 and IL-33 as therapeutic targets in localized fibrosis“
Science Advances 5 (2019): eaay0370full_paper
For Clinical Research:
1 Department of Surgery and Orthopedics, Kungälvs sjukhus, Kungälv, Sweden
2 Department of Hand Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
3 Department of Surgery and Orthopedics, Alingsås lasarett, Alingsås, Sweden
for their joint paper
A. Zachrisson, A. Ibsen Sörensen & J. Strömberg
„Needle fasciotomy for Dupuytren’s contracture- a prospective cohort study of 58 fingers with a median follow-up of 6.5 years“
Journal of Plastic Surgery and Hand Surgery (2019) DOI: 10.1080/2000656X.2019.1693391l
International Dupuytren Award 2019
The International Dupuytren Award 2019 has been funded by donations from members of the former Dupuytren Disease Support Group (DDSG), the Britsh Dupuytren’s Society (BSD) and the International Dupuytren Society (IDS). A big thank you for this great support of Dupuytren research!
Jagdeep Nanchahal
of the Kennedy Institute of Rheumatology, University of Oxford, UK
for
Jagdeep Nanchahal et al.
„Anti-Tumour Necrosis Factor Therapy for Dupuytren’s Disease: A Randomised Dose Response Proof of Concept Phase 2a Clinical Trial„
EBioMedicine 33 (2018) 282–288
International Dupuytren Award 2018
The International Dupuytren Award 2018 has been exclusively funded by personal donations from members of the Dupuytren Disease Support Group (DDSG) and the Britsh Dupuytren’s Society (BSD). A big thank you for this great support of Dupuytren research!
Michael Ng
of the Botnar Research Centre Headington, Oxford, UK,
for
Michael Ng et al.
„A Genome-wide Association Study of Dupuytren Disease Reveals 17 Additional Variants Implicated in Fibrosis„
Am J Hum Genet 101 (2017): 417–427
International Dupuytren Award 2017
For Basic Research:
Sabrina Koh
of the Gillies McIndoe Research Institute, Wellington, New Zealand
for
Sabrina Koh et al.
„Embryonic Stem Cell–like Population in Dupuytren’s Disease„
Plast Reconstr Surg Glob Open 4 (2016): e1064 full_paper
For Clinical Research (two papers jointly):
Jeremy Rodrigues, PhD
of the Nuffield Department of Orthopaedics, University of Oxford, Oxford, UK
for
Jeremy Rodrigues et al.
„Functional outcome and complications following surgery for Dupuytren’s disease: a multi-centre cross-sectional study„
J Hand Surg Eur (2016). pii: 1753193416660045 abstract
Joakim Strömberg, MD
of the Department of Hand Surgery, Sahlgrenska University Hospital, Gothenburg, Sweden
for
Joakim Strömberg et al.
„Comparison of Treatment Outcome After Collagenase and Needle Fasciotomy forDupuytren Contracture: A Randomized, Single-Blinded, Clinical Trial With a 1-Year Follow-Up.„
J Hand Surg Am. 2016 Sep;41(9):873-80. abstract
International Dupuytren Award 2016
For Basic Research:
Latha Satish, PhD
of the Department of Plastic Surgery, University of Pittsburgh, Pittsburgh, USA
for
Latha Satish et al.
„Developing an animal model of Dupuytren’s disease by orthotopic transplantation of human fibroblasts into athymic rat„
BMC Musculoskeletal Disorders (2015) 16:138 full_paper
For Clinical Research (two papers jointly):
(1) Department of Translational Medicine – Hand Surgery, Lund University, Lund, Sweden
(2) Department of Hand & Plastic Surgery, Norrlands University Hospital, Umeå, Sweden
for
Peter Scherman, Per Jenmalm, Lars Dahlin
„One-year results of needle fasciotomy and collagenase injection in treatment of Dupuytren’s contracture: A two-centre prospective randomized clinical trial“
JHS (E) 2015 Dec 1. pii: 1753193415617385 abstract
International Dupuytren Award 2014
Clayton A Peimer, MD
of the College of Human Medicine,
Michigan State University, Marquette, USA,
for
Clayton A Peimer et al.
„Dupuytren Contracture Recurrence Following Treatment with Collagenase Clostridium Histolyticum (CORDLESS Study):
3-Year Data“
J Hand Surg Am 38 (2013) 12-22 abstract
International Dupuytren Award 2013
The Award was presented on 15 March 2013 at the Dupuytren’s Summit in Vienna. The winners of the 2013 International Dupuytren Award are
For Clinical Research: Annet van Rijssen, PhD
of the University Medical Center Groningen, the Netherlands, for
Annet van Rijssen et al.
„Five-Year Results of a Randomized Clinical Trial on Treatment in Dupuytren’s Disease: Percutaneous Needle Fasciotomy versus Limited Fasciectomy„
Plast Reconstr Surg. 2012 Feb;129(2):469-77
For Basic Research: Syed A Iqbal and Christopher Manning (together)
of the Manchester Interdisciplinary Biocentre, University of Manchester, Manchester, United Kingdom, for
SA Iqbal and Ch. Manning et al.
„Identification of Mesenchymal Stem Cells in Perinodular Fat and Skin in Dupuytren’s Disease: A Potential Source of Myofibroblasts with Implications for Pathogenesis and Therapy„
Stem Cells Dev. 2012 Mar 1;21(4):609-22
International Dupuytren Award 2012
The Award 2012 was presented at the Symposium „New Frontiers in Dupuytren Disease“ (Leuven University, Belgium, 31 March 2012). The winner is
Dr. Guido Dolmans
of the University Medical Center Groningen, the Netherlands, for his paper Guido Dolmans et al.
„Wnt Signaling and Dupuytren’s Disease“
N Engl J Med 365 (2011) 307-317
International Dupuytren Award 2011
In 2011 the the Award was given in two categories, for Clinical Research and for Basic Research. It was presented to the winners on 5 November 2011 at the Dupuytren’s Summit in London. The winners of the 2011 International Dupuytren award are
For Clinical Research: Oliver Donaldson
University Hospitals Bristol NHS Foundation Trust, Bristol, UK
for O.W. Donaldson et al. “The association between intraoperative correction of Dupuytren’s disease and residual postoperative contracture“ The Journal of Hand Surgery (European Volume, 2010) 35E: 3: 220–223
For Basic Research: Neda Mosakhani and Mohamed Guled (together)
University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland
for Neda Mosakhani et al. “Unique microRNA profile in Dupuytren’s contracture supports deregulation of b-catenin pathway”Modern Pathology (2010) 23, 1544–1552
International Dupuytren Award 2010
The Award 2010 was presented at the Annual Conference of German Hand Surgeons (DGH 2010). The winner is
Prof. Ilse Degreef
of the Katholicke Universiteit Leuven for her doctoral thesis
„Therapy-resisting Dupuytren’s disease – new perspectives in adjuvant treatment“
