Web sites related to surgery of Dupuytren's contracture

There are many web sites on Dupuytren and you might have visited some of them already. A good overview on Dupuytren's disease is the article by Kristina and Joseph Shaffer in emedicine. A lot of pictures on hand surgery can be found in eatonhand. An article by Lawrence C. Hurst gives a good overview of Dupuytren's disease and related surgery. It is easily readable, has informative pictures, a lot of references to literature, and indicates collagenase as a potential future therapy (Dr. Hurst is involved in the current collagenase research) but disregards NA and radiation therapy: hurst_ontario.

A patient provided us with his disease history history_stefan_horn. We view it as an example of surgery accelerating new Dupuytren and Ledderhose. If the new nodules are operated on again, the surgery cycles get shorter and the surgery itself becomes increasingly difficult due to scar tissue. This doesn't necessarily have to happen but it might and it demonstrates the need for alternative therapies.

 

Research on hand surgery (Dupuytren)

There is a lot of research about hand surgery. Therefore, you might take a look at the American Foundation for Surgery of the Hand, its Journal of Hand Surgery or http://www.journalofsurgicalresearch.com.

Below literature is a (nearly) arbitrary selection:

A comprehensive book, though not really a bargain, is Peter Brenner and Ghazi M. Rayan "Morbus Dupuytren - a concept of surgical treatment" (Springer, New York, 2003). The audience is clearly medical, but there are paragraphs that are easier to read and the book also addresses biochemical and molecular-biological aspects.

A standard text book on Dupuytren surgery is McFarlane RM, McGrouther DA, and Flint MH (Eds.) "Dupuytren's Disease: Biology and Treatment" (Churchill Livingstone, New York, 1990).

Published on the Internet is the thesis of J.P. Moermans, "Place of Segmental Aponeurectomy in the Treatment of Dupuytren’s disease“, Université Libre de Bruxelles, 1997. Link: Thesis_Moermans. Although this thesis naturally focuses on this specific surgical technique, it also has a number of easily readable chapters that deal with general aspects of Dupuytren's disease.

A multi-centre study by the Audit Committee of the (British) BSSH uses subjective data of 1176 patients to assess the outcome surgeries of Dupuytren's contracture: J. J. Dias and J. Braybrooke "Dupuytren's contracture: an audit of the outcomes of surgery" J Hand Surg [Br]. 31 (2006) p 514-21. abstract_Dupuytrens_surgery. The mean follow-up period is 27 months after surgery. "Surgery for Dupuytren's contracture achieved a high rate of full, or almost full, correction in 826 patients (75%) but had a high incidence of post-operative patient-reported complications of 46%." The recurrence rate after 2 years is 15 percent.

 

Research on foot surgery (Ledderhose)

This paper presents experience with surgery of 23 feet and introduces a staging concept for Ledderhose surgery. About 85 percent of the patients were satisfied with the results, the reported recurrence rate is about 10 percent. G. J. Sammarco and P. G. Mangone "Classification and treatment of plantar fibromatosis" Foot Ankle Int. 21 (2000) p 563-9, abstract.

 

Page last modified: 04/16/2008