Literature and Overviews

A summary regarding drug treatment is Janinis J, Patriki M, Vini L, Aravantinos G, Whelan JS, "The pharmacological treatment of aggressive fibromatosis: a systematic review" Ann Oncol. 14/2, (2003) p 181-90. We cannot comment on details but here is the link: drug_overview_article.

Below article is not on a specific therapy, but rather summarizes biochemical influences on myofibroblast contractility, chemical regulation, the influence of growth factors, and the biochemistry of collagen: Badalamente MA, Hurst LC , "The biochemistry of Dupuytren's disease"  Hand Clin. 15 (1999) p 35-42. Both authors were involved in the initial proposal and trials for using collagenase to treat Dupuytren's contracture.

Page last modified: 01/11/2017