Web sites related to surgery of Dupuytren's contracture

There are many web sites on Dupuytren and you might have visited some of them already. A good overview on Dupuytren's disease is the article by Kristina and Joseph Shaffer in emedicine.

A patient provided us with his disease history history_stefan_horn. We view it as an example of surgery accelerating and creating outbreaks of new Dupuytren and Ledderhose disease. If the new nodules are operated on again, the surgery cycles get shorter and the surgery itself becomes increasingly difficult due to scar tissue. This doesn't necessarily have to happen but it might and it demonstrates the need for alternative therapies.


Research on hand surgery (Dupuytren's disease)

There is a lot of research about hand surgery. Therefore, you might take a look at the American Foundation for Surgery of the Hand, its Journal of Hand Surgery or http://www.journalofsurgicalresearch.com.

Below literature is a (nearly) arbitrary selection:

The book Charles Eaton et al. (Eds.) "Dupuytren's Disease and Related Hyperproliferative Disorders" (Springer, Heidelberg/New York 2012) includes many chapters on surgical techniques presenting the current state of knowledge, including new and adjuvant treatments. The book covers anatomy, cell research, genomics, a broad variety of treatment options and the treatment of related diseases. It is also available as ebook.

A comprehensive book, though not really a bargain, is Peter Brenner and Ghazi M. Rayan "Morbus Dupuytren - a concept of surgical treatment" (Springer, New York, 2003). The audience is clearly medical, but there are paragraphs that are easier to read and the book also addresses biochemical and molecular-biological aspects.

A standard text book on Dupuytren surgery is McFarlane RM, McGrouther DA, and Flint MH (Eds.) "Dupuytren's Disease: Biology and Treatment" (Churchill Livingstone, New York, 1990).

Published on the Internet is the thesis of J.P. Moermans, "Place of Segmental Aponeurectomy in the Treatment of Dupuytren’s disease“, Université Libre de Bruxelles, 1997. Link: Thesis_Moermans. Although this thesis naturally focuses on this specific surgical technique, it also has a number of easily readable chapters that deal with general aspects of Dupuytren's disease.

Histological staging may help assessing the probability of disease recurrence and extension after surgery: T. Belaguer et al. "Histological Staging And Dupuytren's Disease Recurrence or Extension after Surgical Treatment: A Retrospective Study of 124 Patients" J Hand Surg Eur. Apr. 24 2009 abstract.

A recent paper on dermofasciectomy is Niloy Roy et al. Fasciectomy and conservative full thickness skin grafting in Dupuytren’s contracture. The fish technique" Acta Orthop. Belg. 72 (2006) p 678-682. Full text pdf.

Reviews of side effects of Dupuytren surgery

A compilation of side effects reported by surgeons is provided by Keith Denkler "Surgical Complications Associated With Fasciectomy for Dupuytren's Disease: A 20-Year Review of the English Literature" ePlasty 10 (2010) E-location ID: e15. Full text. "Data from this study indicate that complications of surgery not only occur frequently but are also varied. ... Patients undergoing fasciectomy for recurrent disease are more likely to experience either digital nerve injury or digital artery injury than patients with primary disease."

A multi-centre study by the Audit Committee of the (British) BSSH uses subjective data of 1176 patients to assess the outcome surgeries of Dupuytren's contracture: J. J. Dias and J. Braybrooke "Dupuytren's contracture: an audit of the outcomes of surgery" J Hand Surg [Br]. 31 (2006) p 514-21. abstract_Dupuytrens_surgery. The mean follow-up period is 27 months after surgery. "Surgery for Dupuytren's contracture achieved a high rate of full, or almost full, correction in 826 patients (75%) but had a high incidence of post-operative patient-reported complications of 46%." The recurrence rate after 2 years is 15 percent (the definition used includes incompletely correcting surgeries).

Hand therapy

Research and literature on hand therapy are unfortunately rare. An overview is provided by Pratt A, Ball C. Dupuytren’s disease – the role of hand therapy. In: Handchirurgie weltweit, editor. Living Textbook of Hand Surgery. Version 2015-01-20. 2014. Full text. See also Patricia Davis and Charles Eaton "Hand therapy for Dupuytren's Contracture" in C. Eaton et al. (Eds.) "Dupuytren's Disease and Related Hyperproliferative Disorders" (Springer, Heidelberg/New York 2012), p 305-316. link.


Research on foot surgery (Ledderhose)

This paper presents experience with surgery of 23 feet and introduces a staging concept for Ledderhose surgery. About 85 percent of the patients were satisfied with the results, the reported recurrence rate is about 10 percent. G. J. Sammarco and P. G. Mangone "Classification and treatment of plantar fibromatosis" Foot Ankle Int. 21 (2000) p 563-9, abstract.


Page last modified: 12/30/2020