Question - would use of the computer mouse for 2-4 hours a day be excessive use of the hand that might trigger Dups? I developed it after I started using the mouse/computer more hours a day. Then again, I was age 69 when I developed it, but that is about the time that most people see it showing up anyway. I can't see it as a cause-effect with what we know at this time, but it looks like a connection. Maybe somebody will do research on this angle. We need to know what triggers it. Then, would people stop playing golf or handball? Would we stop using the mouse? Probably not, but maybe someone would invent a mouse that would cause less stress, if indeed that does happen.

Maybe it is an overactive immune response to the tissue, something similar to psoriasis. The tissue becomes stressed and immune respose takes over and some people have higher predisposition. I have heard( i think on this forum) that the tissue samples of dc have very high collagen percentages and resembles the healing process of the body. Not sure, but i belive dc is most common in the hands than on any other place on the body. Our hands are constantly being stressed by various activities. The only problem is that this condition definately seems to be genetically linked. Very hard to change genes now!

Edited 08/08/09 06:25

With regard to stress & trauma you might have a look at http://www.dupuytren-online.info/dupuytr...ure_trauma.html. There is some indication that specific occupation might trigger Dupuytren's provided there is a genetic tendency to develop it.

Wolfgang