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nodules
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03/17/2010 18:33
mike59 
03/17/2010 18:33
mike59 
Re: nodules

My GP referred me to a hand surgeon. She didn't know much about it.

03/17/2010 22:00
mike59 
03/17/2010 22:00
mike59 
Re: nodules

Next week I see a hand doctor. The physical therapist knew more about this but not that much. I've learned more here. I still have a full range of motion and am able to bend my hand back 30 degrees but I do have cords. The first doctor confirmed DC and said "sorry" like I had just been given a death sentence. I don't care for that doctor much. Thanks again everyone. I have learned a lot.

03/19/2010 18:52
Dalton 
03/19/2010 18:52
Dalton 
Re: nodules

Quote:



Wach,

You said, "Hi Dalton, callie's warning not to interfere with Dupuytren's refers to surgery".

I wasn't referring to surgery. I was referring to anything that might interfere with Dupuytren's, including therapy and lifestyle. My hand was opened up with surgery and there has been zero effect (eight years later) concerning growth of nodules or the spread of Dupuytren's. I still stick to my reasoning that people should be careful with lifestyle influence in the growth of Dupuytren's. I am not sold on the "preventative" treatment to control the advance of Dupuytren's because of the irregularity of the disease.



I'd like to amend my earlier comments. I have recently seen some info substantiating Callie's warning about interfering. From an article at http://www.warrenhammer.com/article-jour...nd-and-foe.html:
"Fibroblasts [cells that give rise to connective tissue], for all the good they do, can create excessive scar tissue in postsurgical situations and are the main culprits in Dupuytren's contracture. Although the underlying cause of this contracture is unknown, fibroblasts intensively proliferate and transform to myofibroblasts, which abnormally remodel the extracellular matrix."

Looking for info on the actual composition of the nodules I found another brief article that further supports the theory: http://www.sciencedirect.com/science?_ob...b4f1e265e8d970f.
"The histological characteristic of Dupuytren's contracture is the presence of numerous nodules among the lamellar structures of the collagen fibres. In the nodules, there are many active fibroblasts which are surrounded by immature fibres and metachromatic substances demonstrated by toluidine blue staining." I'm no scientist, but, this, taken with other portions of the articles indicate to me that anything that damages the nodule tissue can cause "healing" which creates more fibroblasts, leading to scar tissue.

Considering this I have canceled my next PT appointment and will refrain from any aggressive massage to the area.

Edited 03/19/10 20:53

03/19/2010 23:27
mike59 
03/19/2010 23:27
mike59 
Re: nodules

My ring finger on both hands now appears to have some growth - Garrod's Pads? Either it grew verty fast or I never noticed it before. Wild.

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sciencedirect   Dupuytren   substantiating   treatment   disease   contracture   b4f1e265e8d970f   experience   because   stretching   Fibroblasts   surgery   characteristic   naturopathicadvantage   nodules   recommendation   myofibroblasts   metachromatic   preventative   progression