Who is Auxilium? I gather it is not a public company. What is their financial commitment and what kind of financial resources do they have? What is their time frame? what is their distribution capability? What is their history vis a vis other products? If they "commercialize" does that mean they manufacture,advertise, produce etc.? Are they furthering and paying for the effort to get through the regulatory trials? Do they have a marketing arm and capability?
The press release leaves just a few unanswered questions.

This can only help...."*Development* And License Agreement " can only mean that Auxilium is going to kick in to finish the job of getting Collagenase approved for Dups. After all, without that, Dups "Cordease" is worthless. I'll bet you my new SONY flat panel that these guys don't know what's coming regarding NA. While the injections will give us all another choice, let's face it: economically, NA is a Collagenase competitor as they essentially do the same thing. NA, however, will always be far cheeper and from all we've read, at least as effective.

The timing of all this may be to our long term benefit. If Collagenase was good to go *now*, Eaton would probably have been using it and would not have traveled to France. No compelling need. Insurance will cover Collagenase just it now does surgery. It's still going to take these boys a few years to get approval, so there is plenty of time for NA to take hold in the US (though the window is now smaller). The race is back on as to which will prevail. For our sake, let's hope they can coexist. There may be some cases where Collagenase will be more effective that NA. Either way, surgery will be out of vogue and relegated to the category of last resort .

I talked quite a bit to the UCLA doc who will now apparently get funded to run one of the 4 necessary PhaseIII sites. What needs to be ascertained is whether or not the Collagenase will dissolve **only** Dups tissue, or whether it might attack healthy tissue in some cases. The whole idea of the enzyme is that it should only dissolve the Dups cords and leave everything else alone. So far, it's worked perfectly. No other tissue has been effected. However, as you might expect, it's been used sparingly, as **no one knows** exactly how far you can push it. Also, the long term effects are unknown

Well, if it turns out that you can inject a ton of this stuff with complete safety, now you can fix the cases that prove difficult for NA. It will not matter where and how the Dups is growing.....It's toast. (This is at the far end of the Optimistic Scale) We will not know how far this technology can be pushed until someone's hand dissolves just a bit. Then we'll know. I've always wanted this approach added to the arsenal because it has the potential to completely render Dups surgery a thing of the past. Even those who defend surgery will get on board for that.

Man that sounds good. Until I remember they haven't even really started Phase III yet. This is still s-o-o-o far off in the distance.

The potential for Peyronie's and Ledderhose is tremendous. Those conditions can't be helped by something like NA, they would require the dissolving action of Collagenase.

I thought you had talked to the dr at ucla yesterday....i would imagine it might take a few months for money to transfer from such a deal and the new company partnering with them to decide on exactly how it should be spent. But auxilium probably wants to move faster than not if given the choice.