An interesting read on possible future treatment |
|
1
|
1
|
07/03/2013 07:42
Jacinot registered
|
07/03/2013 07:42
Jacinot registered
|
An interesting read on possible future treatment
http://www.google.com/patents/WO2012155212A1?cl=en
Stumbled on this today whilst looking into DUpuytren's treatments.... Watch this space Am interested in other's thoughts/reactions....
|
|
|
08/04/2013 10:27
moondanc
|
08/04/2013 10:27
moondanc
|
Re: An interesting read on possible future treatment
Jaci: http://www.google.com/patents/WO2012155212A1?cl=en
Stumbled on this today whilst looking into DUpuytren's treatments.... Watch this space Am interested in other's thoughts/reactions....
I'm curious why there hasn't been more discussion about this. Any reactions from the Dupuytren Foundation? Diane
|
|
|
08/04/2013 11:21
wach Administrator
|
08/04/2013 11:21
wach Administrator
|
Re: An interesting read on possible future treatment
Not much to discuss, Diane. There are no trials in progress in treating Dupuytren's. This seems to be a patent that wants to cover a potential, theoretical application that does not exist yet and that - for the time being - seems to be not pursued by the pharmaceutical company that owns this patent. Treating DD doesn't seem to be their prime target.
Wolfgang
moondanc:
Jaci: http://www.google.com/patents/WO2012155212A1?cl=en
Stumbled on this today whilst looking into DUpuytren's treatments.... Watch this space Am interested in other's thoughts/reactions....
I'm curious why there hasn't been more discussion about this. Any reactions from the Dupuytren Foundation? Diane
Edited 08/04/13 14:22
|
|
|
08/08/2013 18:38
JohnG
|
08/08/2013 18:38
JohnG
|
Re: An interesting read on possible future treatment
That patent and the treatment using Actilyse (which has as its active ingredient something called altepase) is mentioned on this site, here:
http://www.dupuytren-online.info/dupuytr...s_research.html
When I read that patent, it mentions that 100 patients have been treated in a test.
Searching other websites, it seems that altepase is intended for heart attacks and strokes): http://www.news-medical.net/drugs/Actilyse.aspx
So it seems to me that the pharmaceutical product already exists, and they are attempting to patent an off-label use for it after performing a small trial.
Excerpts:
In the following examples the treatment of a number of patients suffering from Dupuytren's disease (palmar fascial fibromatosis) will be discussed. To date 100 patients suffering from Dupuytren's disease and 4 patients suffering from Ledderhose disease have been treated by the method of the invention using a recombinant tissue plasminogen activator. Specifically, the recombinant tissue plasminogen activator used is Alteplase as part of the commercially available formulation Actilyse™.
In general terms, at least 95% of the patient's suffering from Dupuytren's disease have reported satisfaction with the outcome after one or two rounds of treatment due to a greatly increased range of motion in the affected digits/regions. For those presenting with very pronounced cords or nodules then stripping out of the cord/nodule may be desirable for at least cosmetic reasons. In these cases the stripping procedure is also greatly simplified as a result of the treatment of the invention by comparison to surgery on a Dupuytren's patient who has not had the present treatment. This is as a result of the softening of the tissue.
The outcome of the present treatment was even better for patients suffering from Ledderhose disease in that all patients reported complete satisfaction with the return to function of the affected tissue.
|
|
|
08/21/2015 19:14
dpjcrfsh
|
08/21/2015 19:14
dpjcrfsh
|
Re: An interesting read on possible future treatment
Any way we can get an update on this very promising therapy?
|
|
|
|
1
|
1
|