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AA4500 sucessfull phase 3 trial - webcast
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05/31/2007 22:27
Randy_H 
05/31/2007 22:27
Randy_H 

Re: AA4500 sucessfull phase 3 trial - wecast

Chris, I'm sorry that you feel my comment about the difficulty of recovery form OS was not accurate. We can agree to disagree. However, for the sake of accuracy I'm happy to expand on my remark by saying that for the majority of cases, not for all, recovery is a long term process. And I might add that in your case whatever the discomfort may be it could be well worth it. This disease has put many of us in a tough spot with some hard choices.



Edited at 06/01/07 01:28

05/31/2007 22:31
Mark_D 
05/31/2007 22:31
Mark_D 
Re: AA4500 sucessfull phase 3 trial - wecast

Chris:

I share Wolfgang's opinions.

I have found your posts helpful - although I am strongly in the N.A. camp.

For me (56 years old), N.A. has worked out extremely well. I'll glady do multiple N.A.s rather than face open surgery.

But, I'm glad to learn more about open surgery from folks like you - just in case open surgery some day becomes my last resort.

I think that both you & Diane make good points. I also think that both of you have been civil, and respectful of other people's views, in your respective posts.

Thanks for your input.

Mark



06/01/2007 04:01
DianeS 
06/01/2007 04:01
DianeS 
Re: AA4500 sucessfull phase 3 trial - wecast

Chris, Thanks for sharing your experiences and the advice given by your surgeon. My comments were not intended as a criticism of you or your doctor; rather an expression of how contradictory medical advice can sometimes be. I am so sorry that you have this condition at a young age and wish you the very best in your treatment. Everyone's case is different and I am sure you will make the right decisions.

The comment about amputation came from the fact that two surgeons told me that amputation of my finger might eventually be necessary as the finger might bend again enough to interfere with use of the hand. So Im just relaying what I was told by an orthopedic surgeon and a hand surgeon, neither of whom did NA. It was even mentioned in my file which i read. Both very fine and highly respected doctors. But it scared the beejeezus out of me. I have grown very attached to pinky.

FYI, recovery from two open surgeries was relatively painless. Had a big bottle of pain killers and only used one or two and was able to drive and go about normal activities quickly. But each time the dupuytren's recurred within a year which is why I looked for alternatives. One year after NA, I have less recurrance than after open.

So I know you are not trying to start an argument and I don't wish to either. We all just want to share what we have been told and what we have learned. Sorry if I was too blunt. Keep us updated on your condition and the treatment. you have.

06/02/2007 05:44
Mtloney

not registered

06/02/2007 05:44
Mtloney

not registered

Re: AA4500 sucessfull phase 3 trial - wecast

I think that I am probably more qualified than most ( very very regatiably). i have had 2 dups surgical procedures and now 2 NA, within the last year. These two by Dr. Denkler ( who is Amazing), but what really confuses me is those who confuse NA which the long term cure. At least those of with it at an early age, I am well under 40!. Now the shot (Collagnase, sp??) for those that don't know is purefied GangGreen.... so don't confuse that with NA. And having had two major surgical ops and now 2 NA all on the same finger, AA4500 is the real hope and know Dr. D and he will tell you the same thing.

my $0.02 is we have an alternative with AA4500 and NA for those that want it. I just hope we have a few choices.

06/13/2007 07:03
macphgw 
06/13/2007 07:03
macphgw 
Re: AA4500 sucessfull phase 3 trial - webcast

I had 4 (or possibly 5, I can't remember) surgeries between 1986 and 1991 and believe that the first surgery in my right hand triggered an aggressive advance into 2 previously non involved fingers of that hand.

Subsequent surgeries were done by a better surgeon. Nonetheless, after surgery on the little finger of my left hand the disease appeared in my left index finger (the other fingers are not involved). The contracture in my index finger stabilized quickly, but has progressed within the last couple of months.

I think that any alternatives are good news. Even with the relatively successful surgery in my left hand (my little finger is straighter -far from straight though- and there has been no recurrence in that finger), the function of that hand for guitar playing has never returned to the level it was at immediately before the surgery.

Consequently, I welcome the prospect of any alternative that might have less negative effect on hand function.

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