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Docs in Seattle? Need injection. Steroid? Colagenace?
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03/19/2007 18:36
Joe 
03/19/2007 18:36
Joe 
Docs in Seattle? Need injection. Steroid? Colagenace?

I am having difficulty finding a local doctor to inject my DD lump with Steriod. There is a hand specialist an hour away, but they are 5 weeks out for the first appointment. And I have no idea if they will recommend or do the injection.

I can travel into Seattle or Tacoma if that helps. And I will also be in New Orleans in a few weeks.

When talking to Dr. Kline's office, they mentioned Colagenace, a chemical in trials which is better than steriod's in treating DD Lumps. Does anyone know how long it will be before it is available? Is it available now in Canada perhaps?

Thanks!

03/20/2007 06:53
Wolfgang

not registered

03/20/2007 06:53
Wolfgang

not registered

Re: Docs in Seattle? Need injection. Steroid? Colagenace?

Joe, a few weeks later probably won't make any difference. I would try the hand specialist near by.

Collagenase will still take several years before becoming generally available and I am pretty sure it is not available in Canada or elsewhere either. But that's not an issue because already today you can get the same results with NA. I guess you don't have cords and contraction yet, which is good, but it also means neither collagenase nor NA would be appropriate.

Wolfgang

Quote:



I am having difficulty finding a local doctor to inject my DD lump with Steriod. There is a hand specialist an hour away, but they are 5 weeks out for the first appointment. And I have no idea if they will recommend or do the injection.

I can travel into Seattle or Tacoma if that helps. And I will also be in New Orleans in a few weeks.

When talking to Dr. Kline's office, they mentioned Colagenace, a chemical in trials which is better than steriod's in treating DD Lumps. Does anyone know how long it will be before it is available? Is it available now in Canada perhaps?

Thanks!


03/20/2007 15:37
Joe 
03/20/2007 15:37
Joe 
Re: Docs in Seattle? Need injection. Steroid? Colagenace?

I have a small lump but the skin is pulling towards it and I am very concerned about it getting worse. It’s classic looking but I have no problem extending my ring finger at all. I would be happy to send you an image of it. My e-mail is: joe 1 (at) kineoptics . com

So the Colagenace is only for advanced cases? I was under the assumption that it would reduce or dissolve the Dupuytren’s tissue and catching it in my early stage would almost stop it. I think I got that from the staff at Dr. Kline’s office but I might have misunderstood. Everyone is awaiting it’s release they said.

03/20/2007 17:58
bstenman 
03/20/2007 17:58
bstenman 
Re: Docs in Seattle? Need injection. Steroid? Colagenace?

The injected substance is being licensed by a firm that has no been successful in producing it in sufficient quantity for the clinical trials necessary for FDA approval. The phase III trials according to the people at Stanford are on hold for at least two years. Add a year for the trial and a year for FDA approval and best case is the treatment will be available for your to get sometime in 2011.

In the meantime I would recommend you check out information on radiation treatment which at early stages can halt progression.

Bruce

03/20/2007 21:57
Joe 
03/20/2007 21:57
Joe 
Re: Docs in Seattle? Need injection. Steroid? Colagenace?

So is it possible that radiation may be better than an injection of steriod? What is the series of treatment with progression of DD?

Injection > radiation > NA > open surgery?

03/21/2007 00:51
Randy_H 
03/21/2007 00:51
Randy_H 

Re: Docs in Seattle? Need injection. Steroid? Colagenace?

Injection > radiation > NA > open surgery......*is* a sensible order of progression. However, for Injections and/or radiation to work they be started early. From what Wolfgang reports, radiation may be more *powerful*, but, it is not readily available in the US. It's mostly Germany. I have found cortisone injections to work *very* well, which I had in conjunction with NA. I may seek more. However, again, a lot of US CHS don't do injections as a preventative. The standard care in the US is

Nothing > Open Surgery

This is a shame. I think this state of affairs might change if all CHS were required to have an OS just for the experience. 'Kind of like how shrinks must undergo psychotherapy before they can practice :-)

Meanwhile look into Injection > radiation > NA, regardless of what your CHS might say about these "unproven" approaches. There *is* plenty of proof. It's just that anything short of OS is not currently in vogue with most CHS.

12/13/2007 00:18
firstmerk

not registered

12/13/2007 00:18
firstmerk

not registered

Re: Docs in Seattle? Need injection. Steroid? Colagenace?

As I understand it the collagenase is kind of a chemical alternative to NA. It weakens the cord that is then "snapped" in the same way as NA. If your hand will lay flat on the table you are not a candidate for either.

You may benefit from Kenalog injections. I had the for knuckle pads and they worked for several months but came back after it wore off. Unlike a direct joint injection that is destructive I think you can inject Dup. sites often.

There is a Group Health physician that does NA. He only does in on the palm. Otherwise the closest is Dr. Kline. There may be a Dr. in Vancouver. I have an inquiry about it right now.

Fritz

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conjunction   preventative   information   destructive   appointment   treatment   available   injection   Injections   misunderstood   progression   Colagenace   radiation   psychotherapy   Dupuytren’s   Collagenase   Seattle   specialist   Steroid   contraction