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So it seems I have it...
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02/10/2008 13:07
The_Heathen 
02/10/2008 13:07
The_Heathen 
So it seems I have it...

Hello,

New user here, And nice to have found this place.

My story biefly:

A few years back, I had surgery for at tiny knot in my hand. I had been a drummer for many years and I think that's what provoked it forth a bit prematurely (I was about 29, 32 now). My right hand is fine, I have some hardened tissue around the area where the knot was cut out, but no annoyances related to that, whatsoever. But now, I have this numbing, tingling sensation in my left pinkyfinger (the same sensation you get when you've been sleeping, laying on an arm og perhaps sitting on a leg) and when I massage my elbow, I can feel a reaction down in that particular finger.

1) What should I be doing from here?
2) Since this genetic marker is rather unique (as I understand it), I'm also thinking it can be used to backtrack my own genetic history. How would I go about this? Has anyone here perhaps done this already?
3) How concerned should I be about all the things it's supposedly connected with? (alcoholism, liverdisease Smoking- or drinking activity, Diabetes, Thyroid problems and Epilepsy)

My father died of smoking- and drinking related cancer at 52...

I'm male by the way...

Bye for now,

02/12/2008 06:15
wach 

Administrator

02/12/2008 06:15
wach 

Administrator

Re: So it seems I have it...

1) What should I be doing from here?

A: Maybe nothing? If you have small nodules radiotherapy might be an option that slows down the growth of the nodules and postpones other therapies by maybe 10 or 20 years. It might even stop the disease. There is also a chance that your nodules don' t grow very fast and you can do nothing for the next 10 years and then, if your finger is contracted by 30+ deg you might have NA (or some other therapy that will might be available by then).

2) Since this genetic marker is rather unique (as I understand it), I'm also thinking it can be used to backtrack my own genetic history. How would I go about this? Has anyone here perhaps done this already?

A: depending on where you come from it might not be that unique. Depending on age and region 2 - 40 (or more) percent of men suffer from Dupuytren's. There ought to be better ways to track family history.

3) How concerned should I be about all the things it's supposedly connected with? (alcoholism, liverdisease Smoking- or drinking activity, Diabetes, Thyroid problems and Epilepsy)

A: not too much with respect to Dupuytren's. Those connections probably exist (or maybe theey don't) but there are other, far more important reasons why you should be concerned about alcoholism, liverdisease, smoking, diabetes, thyroid problems, or epilepsy!

02/12/2008 17:15
The_heathen

not registered

02/12/2008 17:15
The_heathen

not registered

Re: So it seems I have it...

Thank you VERY much for your answers.

There's two more questions I have (for now)

1) How common (in rough percentage) is for people with this disease, to also develop Peyronies disease?

2) A link I saw on handcenter.org http://www.ncbi.nlm.nih.gov/pubmed/10597922?dopt=Abstract
[urlhttp://www.ncbi.nlm.nih.gov/pubmed/11781116?dopt=Abstract[/url] speaks of an increased mortality rate of 22%! This sounds very ominous to me

02/12/2008 17:23
The_Heathen 
02/12/2008 17:23
The_Heathen 
Re: So it seems I have it...

Sorry, for some reason I wasn't allowed editing...

There were two links:

http://www.ncbi.nlm.nih.gov/pubmed/11781116?dopt=Abstract and
http://www.ncbi.nlm.nih.gov/pubmed/10597922?dopt=Abstract

Edited at 13.02.08 15:23

02/13/2008 14:40
wach 

Administrator

02/13/2008 14:40
wach 

Administrator

Re: So it seems I have it...


There's two more questions I have (for now)

1) How common (in rough percentage) is for people with this disease, to also develop Peyronies disease?

A: I have seen numbers only for th other direction: about 15 - 20 percent of Peyronie's patients suffer from Dupuytren's as well.

2) A link I saw on handcenter.org http://www.ncbi.nlm.nih.gov/pubmed/10597922?dopt=Abstract
[urlhttp://www.ncbi.nlm.nih.gov/pubmed/11781116?dopt=Abstract[/url] speaks of an increased mortality rate of 22%! This sounds very ominous to me

A: agreed. Though the reason why people die earlier seems to remain unclear. I also wonder whether they seperated men and women when they did their statistics. Men get Dupuytren's earlier, reflected in a higher percentage being treated for Dupuytren's. Men also die earlier. Maybe that's all. I am suspicious about mere statistical correlations. Very high correlation that rain is caused by people using umbrellas.

Wolfgang

02/13/2008 15:25
The_Heathen 
02/13/2008 15:25
The_Heathen 
Re: So it seems I have it...

Ok..

I'm thinking perhaps one of the reasons for the increased mortalityrate is, that people with Dupuytren's are more prone to smoking and drinking like suggested. My father, who I assume passed it one to me, died from alcohol- and drinking related cancer at 52

Does the slight feeling of paralasys people with dupuytren's often experience in one or more fingers, get any worse? Or perhaps even dangerous for the limb in question?

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