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Collagenase
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10/12/2003 23:55
Randy H.

not registered

10/12/2003 23:55
Randy H.

not registered

~dq~Too good to be true?~dq~

"Too good to be true?"

That's seems to be the reaction of many on this site who have watched BioSpecific's project crawl along for years behind schedule due to it's lack of funding for FDA approval of it's collagenase. No FDA approval, no injections. Anyone have some venture capital?

03/23/2004 23:44
Don Westin

not registered

03/23/2004 23:44
Don Westin

not registered

COLLAGENASE

Perhaps a bake sale. But then again, why bother? NA sounds like a better deal anyway.

04/01/2004 23:00
Mike

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04/01/2004 23:00
Mike

not registered

PURCHASING COLLAGENASE IN EUROPE

My dad suffers from DC. His orthopedist has informed him that collagenase is an approved treatment for the condition in Europe. Does anyone know which countries have approved it for sale? Also:

How many injections are needed, and over what period of time?

Is it Rx or OTC in Europe? If Rx, is there any way to still get it?

If I brought some back from Europe, would I run into problems at customs?

Any other advice about purchasing collagenase in Europe would be useful.

Please respond to msgood@rcn.com

Thanks,
Mike

04/01/2004 23:04
George Barbarow

not registered

04/01/2004 23:04
George Barbarow

not registered

NA -Quick, Easy, Painless

Hi Mike:

There is no logical reason to consider collogenase ; as it would likely involve a
series of injections over time.

Needle aponevrotomy is over and done in a bout fifteen minutes with almost no discomfort.

See my testimony on the forum Nov12, 2003 entitled miraculous change.

Also see my photos at:
http://www.picturetrail.com/gallery/view?p=999&gid=3106302&uid=127194&members=1

04/10/2004 23:39
ivan

not registered

04/10/2004 23:39
ivan

not registered

collegenase

I had my injection of collagense 3 years ago, perfect result, and now showing slight signs of contraction again, though a long way from needing another treatment yet.
For the enthusiasts of NA I would like to ask about their knowledge of recurrence rates, say after 3 years.

04/14/2004 23:15
Stage One

not registered

04/14/2004 23:15
Stage One

not registered

Recurrence after NA

I was advisd after my NA procedure that recurrence
was possible/likely within 2 to 4 years ; and,
a repeat NA procedure could be performed when chord
contracture prevented flattening my hand on a table,
once again (30-45 degrees contracture of my "pinkey.")
I used to think that collagenase was "the solution" and
have decided that NA is a more viable remedy becuse of
the efficincy and availability of the procedure.Typically,
a person has one or two visits with a 2-3 day post-op
interlude followed by minor cautions for about three weeks.
The collagenas injections are given over several weeks
as a substitute for the 20-30 minute needle procedure. The
chord is still "snapped" after weakening. From a practical
standpoint, I see little difference and some advantage to
the NA procedure. Factor in the time, expense, travel,
track record, location, expense and make an informed choice.
I encourage any and all with Stage two or more DD/DC to
consult someone. My personal suggestion would be an NA
practitioner from the list at the Lariboisiere site. BTC
may be a viable future option; for the near term NA has a
solid history of favorable outcomes. Check it out!

04/14/2004 23:35
jim h

not registered

04/14/2004 23:35
jim h

not registered

Collagenase

There might be an advantage to Collagenase injections if that treatment requires less training. Not many surgeons are going to travel to France at their own expense to learn NA. Ideally I'd like to drive across town and get the injections during an office visit to a hand surgeon, rather than fly across the country and stay in a motel at my own expense.

04/14/2004 23:23
Roberta

not registered

04/14/2004 23:23
Roberta

not registered

Collagenase

Does anyone know of a Doctor in Washington State that will or does Collagenase injections. I have DC and can still lay a flat hand on table....but the cords are starting to bulge in my palms....just like to cover my self and take care of it early.....safe then sorry .....thanks so much for the great info.........Roberta

04/15/2004 23:40
Ervin

not registered

04/15/2004 23:40
Ervin

not registered

Cordase the Injectable form of Collagenase

This form of treatment is still in the research stage. It is not available for use as yet. It appears that it will be four or five years before FDA approval, if then.

You could go the NA procedure route. Two Doctors do this procedure in the USA: Drs. Edaton and Bourland.

04/15/2004 23:12
j

not registered

04/15/2004 23:12
j

not registered

Proactive spread of NA!!

Yes although we still discuss Collagenase on this forum, hope for its availability is fading because years of FDA Phase III trials lie ahead. Meanwhile if NA goes mainstream in the U.S., the market for it as a Dupuytren's therapy may be greatly reduced. It still has great potential for Peyronie's but I think Biospecifics has been putting all their money into Dupuytren's trials - unfortunately.

As we all know by know, the drug development process in this country is making less sense all the time.

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