Graeme,

Cortisoid shots do no good for Dup's cases that have already begun contracting.

For more info, see the topic entitled 'Forestalling Contracture'. I posted excerpts of the definite study on Kenalog (a cortisoid) injections for Dupuytren's, by Ketcham et al.

On the question of whether a course of cortisoid shots can forestall contracture in cases where it has not yet begun, there seems to be debate. Ketcham's study does not explicitly say that it does, but it seems to pretty strongly imply it. It may be that Ketcham wasn't able or willing to follow up with his study subjects long enough to definitively say.

Dr. Keith Denkler, a CHS here in northern California, posted to the same topic to say he doesn't think it does defer contracture, or at least that there's no proof that it does. But as a matter of fact, I just had Dr. Denkler give me a round of shots for my (not yet contracted) Dup's a few days ago, and he seems to have softened his position to 'maybe it does, not sure.'

Since I only had my first of three rounds of shots a couple of days ago, it's too early for me to testify how effective it is. The effects usually become noticeable after 2 or 3 weeks. Others have written that it does soften and flatten their nodules and cords, and Ketcham claims a high rate of success.

Hope this helps - MML

hi i injured my shoulder whide i was working out and it hurt more then anything so i need a shot of cortizone