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Large Nodule best treatment
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01/30/2013 11:52
wach 

Administrator

01/30/2013 11:52
wach 

Administrator

Re: Large Nodule best treatment

Follow-up data presented at "New Frontiers in Dupuytren Disease", a symposium in Leuve, Belgium, in March 2012 showed that the initial good effect of tamoxifen vanished after a year and recurrence was about the same (if I remember correctly). I would not recommend taking tamoxifen because it has severe side-effects.

Wolfgang

Penny:
...
OR One who uses tamoxifen.


As quoted below by Dr. Eaton on usage of such.

"The most groundbreaking presentation was on the use of preoperative adjuvant tamoxifen to treat patients who had high risk for recurrence after a surgery. This randomized study showed that high-risk patients who had the preoperative treatment before limited fasciectomy for Dupuytren maintained their surgical correction to within about 10 degrees. Patients who were randomized to just the surgical treatment lost an average of 40 degrees of their initial correction.

The study used oral tamoxifen, but I’m considering a trial with topical tamoxifen. The big issues with patients who have aggressive Dupuytren are the extent of skin involvement and the dense relationship between the skin and the fascia as part of the biology. A minimal approach to straighten the fingers, followed by some sort of biologic intervention to maintain those results, would be great. "
Penny

01/30/2013 12:50
Penny 
01/30/2013 12:50
Penny 
Re: Large Nodule best treatment

Thanks for that update on treatments--it is hard to keep up with all the news.
Penny

01/30/2013 14:54
callie 
01/30/2013 14:54
callie 
Re: Large Nodule best treatment

Penny, is there a cord involved with this nodule? What is the rest of your hand like? The other hand? Any contraction?

01/30/2013 20:47
Penny 
01/30/2013 20:47
Penny 
Re: Large Nodule best treatment

This nodule kind of piggybacks on a smaller nodule, which is attached to a cord--I don't think this one is involved with a cord directly. Mostly the ring finger, pinkey and middle finger are somewhat involved. The other hand is mostly corded on the ring finger and middle finger. Both have had NA done and are contracted again to stage 1.
Penny

01/30/2013 21:03
callie 
01/30/2013 21:03
callie 
Re: Large Nodule best treatment

How long ago did you have NA?

01/30/2013 21:11
Penny 
01/30/2013 21:11
Penny 
Re: Large Nodule best treatment

January of 2010

01/31/2013 10:47
Penny 
01/31/2013 10:47
Penny 
Re: Large Nodule best treatment

Not having described my situation very well, I am posting pictures

Attachment
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20130131_052519_resized-1506276424.jpg 20130131_052519_resized-1506276424.jpg (38x)

Mime-Type: image/jpeg, 133 kB

02/02/2013 14:50
Penny 
02/02/2013 14:50
Penny 
Re: Large Nodule best treatment

Had surgery yesterday, typing left handed so keeping it short. Removed the nodule and dup going to pinkey, ring &middle. Was not agressive in getting all the dup, because of the infection. Not in pain.

02/02/2013 16:32
callie 
02/02/2013 16:32
callie 
Re: Large Nodule best treatment

That is interesting. So, the surgery was for Dupuytren's and not just for the infection? Were there cords ("dup going to pinkey, ring &middle"). Please keep in touch with the forum about this. I am really surprised that the surgeon felt it necessary to do surgery.

02/02/2013 19:25
Penny 
02/02/2013 19:25
Penny 
Re: Large Nodule best treatment

The doctor wanted to make sure he got all the infection, so he removed some of the cords and the nodule without removing all for fear it might spread the infection.

Edited 02/02/13 21:25

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infection   groundbreaking   treatments--it   preoperative   presentation   treatment   Seegenschmidt   surgery   “firebreak”   Dupuytren’s   doctor--whatever   infection--and   Dupuytren   week--however   tamoxifen   correction   Implants-Does   randomized   fasciectomy   patients