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my dad
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02/12/2012 14:51
picsbylee 
02/12/2012 14:51
picsbylee 
my dad

My dad has had numerous hand surgeries in the past and thinks it's time for another one. He has seen the NA procedure but it seems like with his scars he may not be a candidate. I'm not sure though. He knows surgery is probably his option. Can someone tell me where to start researching the best place for him? We live in Chicago. THANKS!
Lee

02/12/2012 15:10
hammer 
02/12/2012 15:10
hammer 
Re: my dad

Have him check out Xiaflex.I have lots of scar tissue but this stuff will blast right thru it.I had multiple surgeries also and have had 3 injections on my right hand the last couple months and i m ready to bowl again .Surgery is gonna be old school soon with all the new proceedures out there.Go to www.xiaflex .com and punch in your zip code.It will give you alist of certified Docs in your area.this stuff is slick.good luck.Dave

02/12/2012 15:55
callie 
02/12/2012 15:55
callie 
Re: my dad

Dave,

You said, "Surgery is gonna be old school soon with all the new proceedures out there."

I really wonder if that is good general advice? There are so many successful surgeries with long term quality results. I think this forum is somewhat tainted by those with surgeries that have been less than expected, or those who would abhor the thought of surgery. It is only natural that the tens of thousands of people who have had successful surgeries wouldn't show up on a forum to complain. The problem for Dupuytren's surgery is that it is often a procedure of last resort which makes it more difficult for optimum outcomes. Surgery should take place for contractures of 25-50 degrees, yet many people (including myself) wait until 90 degrees or more contracture.

02/12/2012 17:25
hammer 
02/12/2012 17:25
hammer 
Re: my dad

The down time is to much with surgery and the range of motion.If you dont have a very agressise case then you could have a surgery to clean it out every 10 years if you had to.I coulda and shoulda had 3 or 4 more surgeries because my DD is very agressive.My goal is to get them straight and keep them straight without going uder the knife again.My point is this,my DD will be back in a year even after surgery so why go thru it.Ive had 3 surgeries on my left and it was back in 9 months last time.Maybe the xiaflex will hold it off longer in my case.Every body is different some have one and done.Im not that lucky.Dave

02/13/2012 04:18
Maddie 
02/13/2012 04:18
Maddie 
Re: my dad

Also, many experts seem to think the trauma of surgery can actually be a trigger for new growth.

Maddie

02/13/2012 14:57
callie 
02/13/2012 14:57
callie 
Re: my dad

Maddie,

Is that true? Would that apply to NA (or Xiaflex) when recurrence soon follows the procedure?

I think there might be a correlation/causation of surgery for something other than for Dupuytren's to trigger Dupuytren's. But, I'm not sure that I have heard that surgery for Dupuytren's will trigger Dupuytren's, at least from "experts". Recurrence is not out of the realm of possibility for any procedure involving Dupuytren's.

02/13/2012 15:12
wach 

Administrator

02/13/2012 15:12
wach 

Administrator

Re: my dad

callie,

there is general agreement that a trauma (major wound) can trigger Dupuytren's in people who have the preposition for it (see e.g.http://www.dupuytren-online.info/dupuytr...ure_trauma.html). A surgery is a major wound and the people who undergo Dupuytren's surgery obviously have the tendency to get Dupuytren's. That mechanism and reason for that is not fully understood (as is Dupuytren's) and certainly it's not true for each and everyone, probably only for a minority. But if you are part of this group then Dupuytren's surgery can trigger new disease and require new surgery resulting in an increasing number of surgeries, 5, 10 or more. An example with 5 surgeries (7 in the mean time) is http://www.dupuytren-online.info/history_stefan_horn.htm. Another one is a patient with 15 hand surgeries (Fig. 52.2 of the recent book on Dupuytren's Disease and Related Hyperproloferative Disorders). I myself had a similar experience: within 2 months after my own surgery I developed 6 new, quickly growing nodules in other areas, including the other hand. Your own experience shows the other side of what can happen. You experienced neither disease extension nor recurrence, which is excellent.But maybe not quite typical either?

Wolfgang

callie:
Maddie,

Is that true? Would that apply to NA (or Xiaflex) when recurrence soon follows the procedure?

I think there might be a correlation/causation of surgery for something other than for Dupuytren's to trigger Dupuytren's. But, I'm not sure that I have heard that surgery for Dupuytren's will trigger Dupuytren's, at least from "experts". Recurrence is not out of the realm of possibility for any procedure involving Dupuytren's.

02/13/2012 15:30
callie 
02/13/2012 15:30
callie 
Re: my dad

Wolfgang,

Would that apply to NA (or Xiaflex) when recurrence soon follows the procedure?

Some people might not believe this but heart disease can occur after having heart surgery. The list is endless with every type of procedure when a recurrent disease is involved. I don't understand the point of the comment except to put a damper on having surgery for Dupuytren's. The recurrence rate for surgery is considered less than for many other procedures. I agree that there are exceptions to the norm in any procedure performed for almost anything.

Even "maddie" admitted that Dupuytren's popped up following RT. Does that mean that the RT caused the Dupuytren's to occur?

Wolfgang said, "A surgery is a major wound and the people who undergo Dupuytren's surgery obviously have the tendency to get Dupuytren's." Obviously, I agree, Dupuytren's is a recurrent disease.

Edited 02/13/12 17:47

02/13/2012 16:44
wach 

Administrator

02/13/2012 16:44
wach 

Administrator

Re: my dad

Callie, I was referring to disease extension into other areas, not to recurrence at the operated site. Recurrence after surgery typically takes longer than after NA (and maybe Xiapex) http://www.ncbi.nlm.nih.gov/pubmed/21987045.

Wolfgang

02/13/2012 22:31
callie 
02/13/2012 22:31
callie 
Re: my dad

Thank you for the links. I appreciate the different studies about Dupuytren's. These results were particularly good for the limited fasciectomies.

Partial fasciectomy for Dupuytren's contractures.

"One hundred ninety-six patients with Dupuytren's contractures were treated by partial fasciectomy and adequate postoperative rehabilitation. All patients had flexion contracture of the proximal interphalangeal joint of >20 degrees ; 93 patients had flexion contracture of the associated metacarpophalangeal joint of >30 degrees ; 143 patients had risk factors for Dupuytren's disease. Primary skin closure and splinting were done in all patients. Range of motion was begun by the 1st week. Splinting was discontinued by the 2nd week, followed by night-time splinting until the 8th week. The mean follow-up was 6.6 years (range, 2-9 years). At the latest examination, 72.5% of the patients had complete range of motion of the metacarpophalangeal and proximal interphalangeal joints; 20.2% had 5 degrees -10 degrees of extension deficit and 7.3% had recurrent contractures of >20 degrees at the proximal interphalangeal joint and were subjected to reoperation. Complications included digital neurovascular injury in 5%, complex regional pain syndrome in 10.1%, and wound-healing problems and superficial infections in 15.1%."

http://www.ncbi.nlm.nih.gov/pubmed/19602340

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