Hi-
I am trying to figure out what the lump is on my hand, help. It is in the area where the index finger meets the palm in between the index and middele. it seems to enlarge in the cold?? and also seems to be liquid, when it enlarges i can push it against the bone and it seems to reduce in size. Also there seems to be some discoloration well under the skin (blue or purple). A lot of the other symptoms on this board also meet mine. Any advice?? Thanks.

i have younger twin sisters 29 yrs old under great amounts of stress. Our mother has a neurological didease called Charcott- Marie Tooth syndrome. It's not completeley understood yet. One of my sisters was with me last week and out of no where one of her fingers turned completely white from about the second joint up to the tip. All of her other fingers were pink and warm except for the tip of this one finger. This freaked me out because it was as if that part of her finger was dead. The naxt day she told me that for the first time since this started about 6-9 months ago, that the tips of all har fingers did this, there was no feeling in any of them. Today my other younger twin sister was with me when all of the fingers on her right hand curled straight down to her palm and her thumb was bent inwards. She told me that her hand gets stuck in this position all the time and then shortly releases it self. I personaly dont have what I would concider as seriouse as a problem. Lately I have been having pain in my left toes big toe aches at joint and is loosing sensation at the outer top portion, index toe has a burning sensation a if it has actually been burned on the surace, I also experience this in my left hand ring finger. The toe next to my pinky feels as if something is oulling the nerves and tendons right out of my skin when it is placed in certain positions and my middle toe feels broken? whats going on. All of our Dr. tell us to take motrin and go home. we have all relayrd our family history of neurological disorders to our dr.and none of them are helping our symptoms or runing diagnostic test. Why? I wonder why we are all having these symptoms at the same time. Could it be because we are all under the same emotional stress due to a family crisis.? If so, are they warning signs of more seriouse neuroligical or autoimune disorders that could potentially be treated but are going unrecognised by our Family DR.s If anyone out there can enlighten me on what I have exposed here please write back.

HELP US,

Sisters on there last nerve!

Rachel,
Have the doctors ruled out Raynaud's syndrome? It sounds very much like what you describe. Is it cold when this happens? Raynaud's is a blood circulation problem in which the blood vessels constrict. If that is the problem, it is generally easy to control with medication.

"Raynaud's phenomenon appears to be more common in people who live in colder climates. Once the attack begins, a person may experience three phases of skin color changes (white, blue, and red) in the fingers or toes. ... Raynaud's phenomenon is a disorder that affects the blood vessels in the fingers, toes, ears, and nose ... vary, recent surveys show that Raynaud's phenomenon may affect 5 to 10 ..."