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Medical Publications
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12/29/2006 00:34
kdenkler 
12/29/2006 00:34
kdenkler 
Medical Publications

Here is a link of full-text articles on Dupuytren's available from the national library of medicine "PUBMED Central"
Articles can be old, but they are full text and not just summaries.

Link below

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Search&;db=pmc&term=dupuytren+s&tool=fuzzy&ot=Dupuyten%27s

12/29/2006 00:36
kdenkler 
12/29/2006 00:36
kdenkler 
Re: Medical Publications

Copy and paste entire link into browser.
Highlighted link does not work

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pmc&;;cmd=search&term=dupuytren's

01/03/2007 00:33
jim_h 
01/03/2007 00:33
jim_h 
Re: Medical Publications

Thanks for the link.

I can't help but comment that my reaction, after scanning that list of papers, is that with the exception of needle aponevrotomy, there's been virtually no progress in 40 years, from the point of view of the patient.

Surgical techniques have no doubt improved, but the typical end result of surgery is about the same. There's been research into the genetics and biochemistry - many papers with words like "promising" and "interesting" - but no useful treatment has resulted and there's no indication of any follow-on work in progress.

One can read numerous studies on genetic links, biochemical precursors, cellular changes, and learn about myelofibroblasts, TGF, free radicals and antioxidants but at the end of the day, there's only one thing we can do in 2007 - go in with a sharp instrument and cut away at the bad tissue. Fortunately, in many cases that works reasonably well.


Well there's still AA4500, I guess, which might see the light of day in 5 years if the stock market cooperates.

01/17/2007 23:55
kdenkler 
01/17/2007 23:55
kdenkler 
Re: Medical Publications

Good point Jim H, I agree!
I believe most hand surgeons are waiting for collagenase but till then sharp release is still the most common treatment. Usually by cutting out and now more frequently NA.
Don't forget small knife release was very popular till just after Dupuyten's death till around the 20th century then radical surgeries became popular.
I have Adams book from 1892 that extolls the virtues of subcutaneous release of Dupuyten's. NA is really a varient of his procedure albiet with needles instead of small knives.

William Adams On the treatment of Dupuytren's contraction of the fingers, and on the obliteration of depressed cicatrices by subcutaneous operations. 1879. 2nd edition, 1892.

The suprising reality is that complications from NA are less than with open surgery, which I presented at the ASSH meeting. This truth is even in face of the fact that NA is a blind procedure.

I am grateful for this site and the moderators, and the lack of SPAM.
Thanks
Keith

01/18/2007 09:39
slyporks 
01/18/2007 09:39
slyporks 

Re: Medical Publications

Study from Uppsala Sweden
http://publications.uu.se/theses/abstrac...n=91-554-5262-0

01/20/2007 15:47
Bob_Branstetter 
01/20/2007 15:47
Bob_Branstetter 
Re: Medical Publications

I would also like to thank Kdenkler for the link. It was interesting for me to look at some of the 38 papers that have been written by the surgeon who is treating me, Dr. Lynn D. Ketchum. While I wish that I had access to the complete text of all of the papers, I'm grateful for what is available. In addition to articles on Dermofasciectomy, I also found more information on Triamcinolone injections which I have had on done on my left hand.

While I'm at it, I would also like to thank Wolfgang and Randy for making the old posts from the BioSpecifics Forum available to us on this forum. I had previously tried to wade my way through the Spam on the BioSpecifics site, but I was seldom able to find what I was looking for. I have now spent several hours going through the old Forum Archives and have found it to be a great addition to this forum. This site gets better every day.

03/30/2007 12:54
Wolfgang

not registered

03/30/2007 12:54
Wolfgang

not registered

Free full articles

I find below link useful to spot free full medical articles, not just abstracts:

www.findarticles.com

You can input your seach terms and additionally select "free articles only".

Wolfgang

03/30/2007 12:56
wach 

Administrator

03/30/2007 12:56
wach 

Administrator

issue with long links

Unfortunately our forum software has a bug and can't process long links properly. We were assured that this will be fixed in the next release (as usual). Sorry about that!

Wolfgang

Quote:



Copy and paste entire link into browser.
Highlighted link does not work

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pmc&;;cmd=search&term=dupuytren's


10/24/2007 18:19
kdenkler 
10/24/2007 18:19
kdenkler 
Re: Medical Publications

Here is a nice open access article on Dupuytren's Surgery

http://www.biomedcentral.com/1471-2474/8/60

http://www.biomedcentral.com/content/pdf/1471-2474-8-60.pdf

It is a large series review of 2919 operated fingers for Dupuytren's.
Nerve damage rate with open surgery was 3.7%!

No mention of needle aponeurotomy or radiation

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BioSpecifics   myelofibroblasts   biomedcentral   1471-2474-8-60   Publications   Medical   obliteration   interesting   db=pmc&term=dupuytren   Dermofasciectomy   complications   n=91-554-5262-0   Unfortunately   s&tool=fuzzy&ot=Dupuyten%27s   subcutaneous   cmd=Search&   Triamcinolone   Highlighted   cmd=search&term=dupuytren   articles