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Question: Coenzyme Q10 and collegenase
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07/31/2008 16:19
Megan 
07/31/2008 16:19
Megan 
Question: Coenzyme Q10 and collegenase

Hi everyone,

I am reading a book on menopause in which the author (a physician) suggests that Coenzyme Q10 is one of the most important supplements for a person in mid-life to take. However, she notes that Coenzyme Q10, vitamin E and vitamin C inhibit collagenase enzymes. I surmise from this that it is probably not a great for people with Dupuytren's to take Conenzyme Q10?

Dr. Kline told me that excessivly large amounts of vitamin C should not be taken by people with Dupuytren's, I imagine for the same reason?

Megan

Edited at 07/31/08 19:21

01/25/2009 00:22
snickers 
01/25/2009 00:22
snickers 
Re: Question: Coenzyme Q10 and collegenase

Megan,

I find this very interesting. I started taking CoQ10 last year and was diagnosed later in the year with DC. However, I have also been taking an epilepsy medication for the past two year for a different condition. I have also read on several websites that you have a slightly higher chance of getting DC if you are being treated for epilepsy. I wonder if taking the CoQ10 and epilepsy medication accelerated my DC. My nodules first appeared in the summer and I was diagnosed in October. Since then, it has spread to a second finger.

01/25/2009 15:27
Wolfgang

not registered

01/25/2009 15:27
Wolfgang

not registered

Phenobarbital and Ledderhose

Hi Snickers, phenobarbital seems to also foster Ledderhose, see http://www.dupuytren-online.info/ledderhose_therapies.html.

Wolfgang

01/26/2009 15:44
debrr 
01/26/2009 15:44
debrr 
Re: Question: Coenzyme Q10 and collegenase

Just saw this post. I would love an answer to the CO-Q 10 as well. I am also taking 1000 mg of Vitamin C. I sure don't won't to do anything to aggravate this disease. Does anyone know about this?
Thanks!

01/26/2009 21:05
Megan 
01/26/2009 21:05
Megan 
Re: Question: Coenzyme Q10 and collegenase

Hi Debrr,

I asked Dr. Kline about this when I saw him in November. I'm also taking 1000 mg of C, the reason being that I'm taking NAC (N-Acetyl-L-Cysteine) and a couple of websites I looked at said if you take NAC, you need to take twice to three times that amount of Vitamin C (I'd like to know if anyone on this site could confirm this).

Dr. Kline said he believed it would have to be really large amounts of Vitamin C (I think he said something like 10,000 mg daily). Whatever it was, he felt like 1000 was fine for me to take.

Megan

01/26/2009 23:09
debrr 
01/26/2009 23:09
debrr 
Re: Question: Coenzyme Q10 and collegenase

Thanks for your answer Megan! I didn't know you needed more Vitamin C with NAC. So thanks for informing me on that. I am also taking NAC. How much are you taking? For how long? Do you see any difference?

Is anyone taking CO-Q 10 with NAC? I am suppose to take it I guess because I am on statins. But I would quit taking it in a heartbeat it I knew it would aggravated LD!

01/28/2009 04:38
Megan 
01/28/2009 04:38
Megan 
Re: Question: Coenzyme Q10 and collegenase

Quote:



Hi Debrr!

I am taking 600 mg of NAC per day. I've been taking it since June, 2008. Hard to say whether it is working, because I've just finished radiation, plus I've had two kenalog injections into my nodule. As you can see, I'm hitting this from all angles!

Megan


Edited 01/28/09 06:39

01/28/2009 04:47
newman 
01/28/2009 04:47
newman 

Re: Question: Coenzyme Q10 and collegenase

Hi Megan Australia Calling. When did you have the injection of kenalog. Before or after RT. Was it Kenalog 40 with Lidocaine 2% What was the time frame between injections. Regards.

01/28/2009 05:25
Megan 
01/28/2009 05:25
Megan 
Re: Question: Coenzyme Q10 and collegenase

Hello Newman,

I had kenalog (not sure of any other specifics) and Lidocaine in June 2008 and another set of injections the Friday I finished the radiation therapy, in November 2008. I went directly from my last radiation appointment over to Dr. Kline's for the kenalog injection; Dr. Kuhn, the radiation oncologist, said it would be OK.

It seems to have flattened and it is not tender like it was previously.

Megan

01/28/2009 06:03
newman 
01/28/2009 06:03
newman 

Re: Question: Coenzyme Q10 and collegenase

Thanks Megan Australia Calling. I had RT on a nodule on my left index (30 Gy ) which stopped all the itchiness and growing sensation etc.The nodule has softened andwhen I apply pressure it moves and reduces, but then returns. In Oct/08 I spoke with Prof Seegenschmiedt about having an injection of Kenalog. He was not opposed to it . I got a referal but have been waiting. Having read your post I will now act . Regards.

Edited 01/28/09 08:04

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collegenase   Question   N-Acetyl-L-Cysteine   collagenase   accelerated   kenalog   Phenobarbital   injection   vitamin   Seegenschmiedt   dupuytren-online   difference   supplements   medication   injections   appointment   radiation   Ledderhose   Coenzyme   interesting