What is considered rapid progression? |
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10/02/2018 23:59
Susan_Surdow
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10/02/2018 23:59
Susan_Surdow
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What is considered rapid progression?
I have been doing some online research and see 3 subtypes of Dupuytrens disease. I am trying to figure out if I am type 1 or type 2. What I can't find is what would be qualify as a "rapid progression". My case....I first noticed nodules Thanksgiving Day 2017 (November) at the age of 49. Currently, 10 months later, I have a 10 degree contracture of my left pinky at the second knuckle. Yes, there is family history. My maternal grandfather had 3 finger on his right hand with severe contractures. They used to call it "trigger finger" because he always looked like he was shooting a gun. My younger brother also has a significant contracture of his right ring finger. I am trying to decide if/when to start treatment and what my best options might be. I have a feeling treatment modality might be affected by how quickly contractures form.
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10/03/2018 10:15
wach  Administrator
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10/03/2018 10:15
wach  Administrator
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Re: What is considered rapid progression?
Hi Susan,
welcome to our forum!
Regarding the Dupuytren subtypes, please explain what type 1 and 2 mean. If you are referring to stages of Dupuytren's https://www.dupuytren-online.info/dupuyt..._therapies.html then you are probably in stage N/1 or 1. Stage 2 would be an extension deficit bigger than 45 degrees.
Dupuytren contracture usually develops slowly, it might take 3-5 years to develop a contracture, many people with mild symptoms of Dupuytren's (nodules in the palm) never develop any contracture at all and need no treatment. If your finger contracted already within one year then I would consider it rapid progression. To slow down progression radiotherapy might be a means. I would not have the full hand irradiated but only the nodule/cord that you have (with some margin around). This allows to treat other fingers later should a new nodule develop there. If you want no radiotherapy you could either wear a night splint https://www.dupuytren-online.info/dupuyt...-splinting.html to avoid further contracture or try needle fasciotomy (NA). Some doctors are already treating fingers with small extension deficits.
If "trigger finger" was just a nick name for your grandfather's condition and bis fingers were bent permanantly, he probably suffered from Dupuytren's. But "trigger finger" is also a name for a different disease. A trigger finger is temporarily fixed in a bent position. This happens instantly and can go away again quickly as well. Dupuytren's is (usually) slowly developing and results in a permanent extension deficit, i.e. the inability to fully stretch the affected finger.
Should your brother consider treatment of his finger he might explore the minimally invasive NA https://www.dupuytren-online.info/needle_aponeurotomy.html and collagenase injection https://www.dupuytren-online.info/dupuytren_collagenase.html.
BTW, where do you live? Unfortunately not all treatments are available everywhere.
Wolfgang
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10/11/2018 21:44
Susan_Surdow
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10/11/2018 21:44
Susan_Surdow
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Re: What is considered rapid progression?
By types of Dupuytren's disease, I mean there are 3 different types according to the Dupuytren's Foundation. https://dupuytrens.org/three-types-of-dupuytren-disease/
My grandfather did have Dupuytren's disease not trigger finger. His kids called it a trigger finger because he had contractures of last 3 digits on his right hand.
I live in the NY metropolitan/Long Island area and am a little concerned about this minor contracture because it developed in under a year from discovery of the first nodule.. So I am wondering if that is considered "rapid progression". I have also recently found a nodule on my other palm and slight roping of the corresponding tendon on that hand.
Edited 10/11/18 22:46
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11/22/2018 23:42
Prof.Seegenschmiedt
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11/22/2018 23:42
Prof.Seegenschmiedt

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Re: What is considered rapid progression?
From the perspective of radiation therapy "rapid progression" is considered when the following changes of symptoms / signs occur and progress within a period of 3 - 6 months:
(1) NODULES: Change (= increase) of number of detected nodules; increase of size of nodules; involvement of other finger rays than the previously involved finger ray; change of the consistency of the nodules (soft - medium - hard)
(2) CORDS: Development of a first cord or new cords; increase of the length of the cord
(3) FINGER INVOLVEMENT: Spread of new nodules and cords to the fingers
(4) CHANGE OF HAND SURFACE PROFILE: Development of new wrinkles, folds, pit holes etc.
(5) CHANGE OF HAND & FINGER FUNCTION: Increased tension or pressure feeling; increase of pain; itching or other sensations; developing of finger "bending"; unable to perform the "Table Top Test"
(6) SUBJECTIVE EVALUATION: Evaluation and changes of the above symptoms may be additionally and subjectively graded on a scale of 1 - 10.
(7) OBJECTIVE EVALUATION: Take photographs in defined intervals (e.g. evry 3 months) under standard light conditions and mark your palpated or observed changes of the hand palm on the skin with a marker pin. Compare the photographs.
The evaluation should be repeated about every months, thus, that changes may be recorded for about 3 time intervals over a period of at least 3 months.
Patients should receive radiotherapy only if progression - using the above criteria - has been documented for at least 3 months; I personally prefer even an observation period of 6 months, as a "spontaneous stand still" may be possible. ----------------------------------------------------------------------------------------------------------
With gratitude for all affected patients & medical colleagues who help to advance patient care.Prof. S.
Edited 11/23/18 08:18
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